Results 81 to 90 of about 426,270 (312)

Hydrogen sulfide repairs testicular damage induced by heat stress in rats

FEBS Open Bio, EarlyView.
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo, Yupeng Yin, Susu Guo, Xiaoyan Chen, Suyan Xie, Shiqin Chen, Yan Huang   +6 more
wiley   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Nuclear Ethics Revisited [PDF]

, 2023
Joseph S. Nye
openalex   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Protocol for imaging nuclear pore complexes on isolated nuclei of zebrafish early embryos by field emission scanning electron microscopy

STAR Protocols, 2023
Summary: Here, we present a protocol to observe the three-dimensional surface of nuclear pore complexes (NPCs) of vertebrate early embryos by field emission scanning electron microscopy (FESEM).
Weimin Shen, Anming Meng
doaj  

Nuclear Energy: An Ethical Use of Resources

IIUM Engineering Journal, 2012
Energy is the lifeblood of development, but its amount is finite. It can neither be created nor destroyed; but it can be converted from one form to another. The conversion changes the state of the resources and the change generally is not reversible. Nuclear energy steadily contributes about sixteen percent to global total electricity demand.
openaire   +4 more sources

Protocol for IPO11 deletion and re-expression in H460 lung cancer cells using CRISPR-Cas9 and plasmid transfection

STAR Protocols, 2023
Summary: Exploring the essential role of Importin 11 (IPO11) in the nuclear translocation of its potential cargo proteins requires an efficient means of IPO11 deletion and re-expression.
Yarui Zhang, Guomin Ou, Zhou Zhou, Jingdong Wang, Hongying Yang   +4 more
doaj  

Protocol for constructing a hierarchical host-guest supramolecular self-assembly system in water

STAR Protocols, 2023
Summary: Here, we present a protocol for the construction of a hierarchical host-guest supramolecular self-assembly system in water. We describe steps for determining the binding levels and capturing the morphologies of hierarchical self-assembly.
Xiao Chen, Xu-Man Chen, Quan Li
doaj  

Ethics Report on Interspecies Somatic Cell Nuclear Transfer Research [PDF]

, 2009
Loane Skene, Giuseppe Testa, Insoo Hyun, Kyu Won Jung, Angela McNab, John A. Robertson, Christopher Thomas Scott, Jan Helge Solbakk, Patrick Taylor, Laurie Zoloth   +9 more
openalex   +1 more source

Teaching And Assessment Of Professional Ethics In The Nuclear Engineering Education According To The Abet Engineering Criteria [PDF]

, 2020
Waleed H. Abulfaraj, Mohamed Hassan
openalex   +1 more source