Results 91 to 100 of about 1,404,159 (323)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Monte Carlo modeling and simulation of electron beam irradiation optimization for screwworm fly eradication through sterile insect technique

Nuclear Engineering and Technology
This study defined the basic requirements of an electron beam irradiation system to deliver an optimal dose uniformity ratio (DUR) for screwworm pupal irradiation for sterile insect technique (SIT) application through radiation physics modeling and ...
Dany Mulyana, Sunil S. Chirayath, Suresh D. Pillai, Keyan Zhu-Salzman, Aaron M. Tarone, John B. Welch, Pamela L. Phillips, Jennifer L. Elster   +7 more
doaj   +1 more source

Nuclear transplantation experiments in Amphibia [PDF]

Nature, 1978
Cloning: Nuclear Transplantation in Amphibia. By R. G. McKinnell. (University of Minnesota Press: Minneapolis, 1978.) $22.50.
openaire   +1 more source

Structure functions for light nuclei

, 2010
We discuss the nuclear EMC effect with particular emphasis on recent data for light nuclei including 2H, 3He, 4He, 9Be, 12C and 14N. In order to verify the consistency of available data, we calculate the \chi^2 deviation between different data sets.
B. L. Ioffe, R. Petti, S. A. Kulagin
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Study on Influence of Nitric Acid Concentration on Criticality Safety

Yuanzineng kexue jishu
The nuclear criticality safety issue in spent fuel reprocessing facilities is closely related to the main process and is almost equally important. It is closely related to the design and operation of reprocessing facilities.
WANG Fan, ZHU Qingfu, XIA Zhaodong, ZHOU Qi, CHEN Xiaoxian, CHENG Yuting, LIANG Shuhong, LI Hang, ZHANG Zhifeng, LIU Yang
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Nuclear symmetry energy in calcium-calcium collisions (INDRA-VAMOS)

EPJ Web of Conferences, 2012
The density dependence of the symmetry energy is of great interest to many fields of nuclear physics and nuclear astro-physics. The E503 INDRA-VAMOS experiment performed at GANIL in 2007 is intended to provide further sub-saturation constraints using ...
Chartier M., Boisjoli M., Wigg P.C., Chbihi A., Lemmon R., Frankland J.D., Le Neindre N., Marini P.   +7 more
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source