Results 81 to 90 of about 592,569 (248)
Design and implementation of an RDMA-based data transmission system prototype for ETF
Nuclear Engineering and TechnologyData transmission is crucial in nuclear physics experiments. As the size of detectors and measurement data increases, traditional Ethernet protocols have become insufficient for performance requirements.
Yuqiao Zhang +8 more
doaj +1 more source
Reduced neutron widths in the nuclear data ensemble: Experiment andtheory do not agree
EPJ Web of Conferences, 2010 I have analyzed reduced neutron widths (Γ0n) for the subset of 1245 resonances in the nuclear data ensemble (NDE) for which they have been reported.
Koehler P.E.
doaj +1 more source
Dose effect of gamma radiation on reliable voltage pulse measurement in nuclear fusion experiments
, 2020 Nenad Kartalović +3 more
openalex +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Status of high intensity low energy injector for Jinping underground nuclear astrophysics experiments [PDF]
, 2018 Quantan Wu +8 more
openalex +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Editorial: Advancements in nuclear and irradiation experiments
Frontiers in Energy Research, 2023 Richard Howard
doaj +1 more source