Results 11 to 20 of about 88,381 (100)

Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy 纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用

Journal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023
Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang, Wai Kit Chu, Tsz Kin Ng, Shaolang Chen, Jiajian Liang, Chong‐Bo Chen, Yanxuan Xu, Biyao Xie, Shuping Ke, Qingping Liu, Weiqi Chen, Dingguo Huang   +11 more
wiley   +1 more source

CatMass: software for calculating optimal sample masses for X‐ray absorption spectroscopy experiments involving complex sample compositions

Journal of Synchrotron Radiation, Volume 30, Issue 5, Page 1023-1029, September 2023., 2023
CatMass is a new software for calculating the optimal sample mass of samples with complex compositions (e.g. a supported metal catalyst mixed with a diluent) for X‐ray absorption and X‐ray scattering experiments with supplemental results to guide experimental design and collection geometry.This paper presents software for calculating the optimal mass ...
Jorge E. Perez-Aguilar, Ash Caine, Simon R. Bare, Adam S. Hoffman   +3 more
wiley   +1 more source

Tumour cells are sensitised to ferroptosis via RB1CC1‐mediated transcriptional reprogramming

Clinical and Translational Medicine, Volume 12, Issue 2, February 2022., 2022
Nuclear translocation of RB1CC1 sensitises tumour cells to ferroptosis. Phosphorylation at S537 by JNK is prerequisite for RB1CC1 to translocate into nucleus. RB1CC1 recruits ELP3 to reinforce H4K12Ac within ferroptosis‐associated enhancers, and RB1CC1 activates transcriptional reprogramming to enhance mitochondrial function. RB1CC1 is an indispensible
Xiangfei Xue, Lifang Ma, Xiao Zhang, Xin Xu, Susu Guo, Yikun Wang, Shiyu Qiu, Jiangtao Cui, Wanxin Guo, Yongchun Yu, Fenyong Sun, Yi Shi, Jiayi Wang   +12 more
wiley   +1 more source

Gastrodin induces lysosomal biogenesis and autophagy to prevent the formation of foam cells via AMPK‐FoxO1‐TFEB signalling axis

Journal of Cellular and Molecular Medicine, Volume 25, Issue 12, Page 5769-5781, June 2021., 2021
Abstract Abnormal accumulation of lipids and massive deposition of foam cells is a primary event in the pathogenesis of atherosclerosis. Recent studies have demonstrated that autophagy and lysosomal function of atherosclerotic macrophages are impaired, which exacerbates the accumulation of lipid in macrophages and formation of foam cells.
Jun Tao, Ping Yang, Liqiu Xie, Yuwei Pu, Jiazhi Guo, Jianlin Jiao, Lin Sun, Di Lu   +7 more
wiley   +1 more source

Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH‐Induced Bone Anabolism in Male Mice

Journal of Bone and Mineral Research, Volume 36, Issue 3, Page 604-616, March 2021., 2021
ABSTRACT Skeletal homeostasis critically depends on the proper anabolic functioning of osteolineage cells. Proliferation and matrix synthesis are highly demanding in terms of biosynthesis and bioenergetics, but the nutritional requirements that support these processes in bone‐forming cells are not fully understood.
Steve Stegen, Claire‐Sophie Devignes, Sophie Torrekens, Riet Van Looveren, Peter Carmeliet, Geert Carmeliet   +5 more
wiley   +1 more source

A promising PET tracer candidate targeting α‐synuclein inclusions

, 2023
Clinical and Translational Medicine, Volume 13, Issue 9, September 2023.
Jie Xiang, Zhentao Zhang, Keqiang Ye
wiley   +1 more source

Neutrinoless Double Beta Decay, the Inverted Hierarchy and Precision Determination of theta(12) [PDF]

, 2011
Ruling out the inverted neutrino hierarchy with neutrinoless double beta decay experiments is possible if a limit on the effective mass below the minimal theoretically possible value is reached.
A. Giuliani,, Alexander Dueck, C. Nones, Kai Zuber, Werner Rodejohann, Y. Takeuchi   +5 more
core   +2 more sources

Heavy-flavour and quarkonium production in the LHC era: from proton-proton to heavy-ion collisions [PDF]

, 2015
This report reviews the study of open heavy-flavour and quarkonium production in high-energy hadronic collisions, as tools to investigate fundamental aspects of Quantum Chromodynamics, from the proton and nucleus structure at high energy to deconfinement
Andronic, A., Arleo, F., Arnaldi, R., Beraudo, A., Bruna, E., Caffarri, D., Contreras, J. G., Dahms, T., Dainese, A., de Cassagnac, R. Granier, del Valle, Z. Conesa, Djordjevic, M., Ferreiro, E. G., Fujii, H., Gossiaux, P. B., Hadjidakis, C., He, M., Horowitz, W. A., Kolevatov, R., Kopeliovich, B. Z., Lansberg, J. P., Lombardo, M. P., Lourenco, C., Martinez-Garcia, G., Massacrier, L., Mironov, C., Mischke, A., Nahrgang, M., Nguyen, M., Nystrand, J., Peigne, S., Porteboeuf-Houssais, S., Potashnikova, I. K., Rakotozafindrabe, A., Rapp, R., Robbe, P., Rosati, M., Rosnet, P., Satz, H., Schicker, R., Schienbein, I., Schmidt, I., Scomparin, E., Sharma, R., Stachel, J., Stocco, D., Strickland, M., Tieulent, R., Trzeciak, B. A., Uphoff, J., van Hees, H., Vitev, I., Vogt, R., Watanabe, K., Woehri, H., Zhuang, P.   +55 more
core   +7 more sources

Nuclear Track Detectors. Searches for Exotic Particles [PDF]

, 2008
We used Nuclear Track Detectors (NTD) CR39 and Makrofol for many purposes: i) Exposures at the SPS and at lower energy accelerator heavy ion beams for calibration purposes and for fragmentation studies. ii) Searches for GUT and Intermediate Mass Magnetic
A. Noll, D. Nikezic, E. Vilela, E. Witten, G. Abbiendi, G. Giacomelli, G. Giacomelli, H.L. Bradt, J. Derkaoui, L. Patrizii, M. Ambrosio, M. Ambrosio, M. Ambrosio, P.B. Price, P.B. Price, S. Balestra, S. Balestra, S. Cecchini, S. Cecchini, S. Cecchini, S. Coleman, S. Kodaira, S. Manzoor, S. Orito, S.A. Durrani, T.W. Kephart, V. Togo   +26 more
core   +2 more sources

Neutrino-nucleus reactions in the energy range 1-100 MeV [PDF]

, 2006
We review some salient aspects of calculations of the neutrino-nucleus reaction cross sections in the low energy range (1-100 MeV).Comment: 6 pages:Invited talk at NuInt05 (Fourth International Workshop on Neutrino- Nucleus Interactions in the Few-GeV ...
Ahmad, Albert, Ando, Ando, Arima, Auerbach, Beane, Benhar, Brandow, Brown, Bugaev, Butler, Butler, Carlson, Chemtob, Chou, Cohen, Ellis, Engel, Fukugita, Gaisser, Haxton, Haxton, Hayes, Ivanov, Jachowicz, Jenkins, K. Kubodera, Kanada-En'yo, Kaplan, Kolbe, Krmpotić, Kubodera, Kuramoto, Langanke, MacDonald, Machleidt, Marcucci, Marcucci, Nakamura, Nakamura, Navrátil, Nieves, Park, Park, Park, Park, S. Nakamura, Smith, Stetcu, T. Sato, Towner, Towner, Weinberg, Wilkinson, Wiringa, Wiringa   +56 more
core   +1 more source