Results 11 to 20 of about 3,127 (137)

Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy 纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023
Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang   +11 more
wiley   +1 more source

CatMass: software for calculating optimal sample masses for X‐ray absorption spectroscopy experiments involving complex sample compositions

open access: yesJournal of Synchrotron Radiation, Volume 30, Issue 5, Page 1023-1029, September 2023., 2023
CatMass is a new software for calculating the optimal sample mass of samples with complex compositions (e.g. a supported metal catalyst mixed with a diluent) for X‐ray absorption and X‐ray scattering experiments with supplemental results to guide experimental design and collection geometry.This paper presents software for calculating the optimal mass ...
Jorge E. Perez-Aguilar   +3 more
wiley   +1 more source

Tumour cells are sensitised to ferroptosis via RB1CC1‐mediated transcriptional reprogramming

open access: yesClinical and Translational Medicine, Volume 12, Issue 2, February 2022., 2022
Nuclear translocation of RB1CC1 sensitises tumour cells to ferroptosis. Phosphorylation at S537 by JNK is prerequisite for RB1CC1 to translocate into nucleus. RB1CC1 recruits ELP3 to reinforce H4K12Ac within ferroptosis‐associated enhancers, and RB1CC1 activates transcriptional reprogramming to enhance mitochondrial function. RB1CC1 is an indispensible
Xiangfei Xue   +12 more
wiley   +1 more source

Gastrodin induces lysosomal biogenesis and autophagy to prevent the formation of foam cells via AMPK‐FoxO1‐TFEB signalling axis

open access: yesJournal of Cellular and Molecular Medicine, Volume 25, Issue 12, Page 5769-5781, June 2021., 2021
Abstract Abnormal accumulation of lipids and massive deposition of foam cells is a primary event in the pathogenesis of atherosclerosis. Recent studies have demonstrated that autophagy and lysosomal function of atherosclerotic macrophages are impaired, which exacerbates the accumulation of lipid in macrophages and formation of foam cells.
Jun Tao   +7 more
wiley   +1 more source

The T2K experiment [PDF]

open access: yes, 2011
The T2K experiment is a long baseline neutrino oscillation experiment. Its main goal is to measure the last unknown lepton sector mixing angle θ13 by observing νe appearance in a νμ beam.
A. K. Ichikawa   +999 more
core   +1 more source

Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH‐Induced Bone Anabolism in Male Mice

open access: yesJournal of Bone and Mineral Research, Volume 36, Issue 3, Page 604-616, March 2021., 2021
ABSTRACT Skeletal homeostasis critically depends on the proper anabolic functioning of osteolineage cells. Proliferation and matrix synthesis are highly demanding in terms of biosynthesis and bioenergetics, but the nutritional requirements that support these processes in bone‐forming cells are not fully understood.
Steve Stegen   +5 more
wiley   +1 more source

A promising PET tracer candidate targeting α‐synuclein inclusions

open access: yes, 2023
Clinical and Translational Medicine, Volume 13, Issue 9, September 2023.
Jie Xiang, Zhentao Zhang, Keqiang Ye
wiley   +1 more source

Results on hyperon production from the NA57 experiment [PDF]

open access: yes, 2004
Recent results on hyperon production in Pb--Pb collisions from the NA57 experiment are reported. Strangeness enhancement and the transverse mass spectra properties at 158 GeV per nucleon are described.Recent results on hyperon production in Pb--Pb ...
Jacholkowski, A.   +86 more
core   +1 more source

Photoproduction of axion-like particles [PDF]

open access: yes, 2019
We explore the sensitivity of photon-beam experiments to axionlike particles (ALPs) with QCD-scale masses whose dominant coupling to the standard model is either to photons or gluons.
Fanelli, Cristiano   +3 more
core   +1 more source

Photo-excitation of nucleon resonances from complex nuclei [PDF]

open access: yes, 2006
Photoproduction of [n] mesons off 12C, 40Ca, 93Nb, and natPb nuclei has been measured with the tagged-photon-beam technique for incident photon energies between 0.6 and 2.2 GeV.
Mertens, Thierry
core   +1 more source

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