Results 11 to 20 of about 93,848 (168)

Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy 纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用

Journal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023
Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang, Wai Kit Chu, Tsz Kin Ng, Shaolang Chen, Jiajian Liang, Chong‐Bo Chen, Yanxuan Xu, Biyao Xie, Shuping Ke, Qingping Liu, Weiqi Chen, Dingguo Huang   +11 more
wiley   +1 more source

CatMass: software for calculating optimal sample masses for X‐ray absorption spectroscopy experiments involving complex sample compositions

Journal of Synchrotron Radiation, Volume 30, Issue 5, Page 1023-1029, September 2023., 2023
CatMass is a new software for calculating the optimal sample mass of samples with complex compositions (e.g. a supported metal catalyst mixed with a diluent) for X‐ray absorption and X‐ray scattering experiments with supplemental results to guide experimental design and collection geometry.This paper presents software for calculating the optimal mass ...
Jorge E. Perez-Aguilar, Ash Caine, Simon R. Bare, Adam S. Hoffman   +3 more
wiley   +1 more source

Tumour cells are sensitised to ferroptosis via RB1CC1‐mediated transcriptional reprogramming

Clinical and Translational Medicine, Volume 12, Issue 2, February 2022., 2022
Nuclear translocation of RB1CC1 sensitises tumour cells to ferroptosis. Phosphorylation at S537 by JNK is prerequisite for RB1CC1 to translocate into nucleus. RB1CC1 recruits ELP3 to reinforce H4K12Ac within ferroptosis‐associated enhancers, and RB1CC1 activates transcriptional reprogramming to enhance mitochondrial function. RB1CC1 is an indispensible
Xiangfei Xue, Lifang Ma, Xiao Zhang, Xin Xu, Susu Guo, Yikun Wang, Shiyu Qiu, Jiangtao Cui, Wanxin Guo, Yongchun Yu, Fenyong Sun, Yi Shi, Jiayi Wang   +12 more
wiley   +1 more source

Gastrodin induces lysosomal biogenesis and autophagy to prevent the formation of foam cells via AMPK‐FoxO1‐TFEB signalling axis

Journal of Cellular and Molecular Medicine, Volume 25, Issue 12, Page 5769-5781, June 2021., 2021
Abstract Abnormal accumulation of lipids and massive deposition of foam cells is a primary event in the pathogenesis of atherosclerosis. Recent studies have demonstrated that autophagy and lysosomal function of atherosclerotic macrophages are impaired, which exacerbates the accumulation of lipid in macrophages and formation of foam cells.
Jun Tao, Ping Yang, Liqiu Xie, Yuwei Pu, Jiazhi Guo, Jianlin Jiao, Lin Sun, Di Lu   +7 more
wiley   +1 more source

Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH‐Induced Bone Anabolism in Male Mice

Journal of Bone and Mineral Research, Volume 36, Issue 3, Page 604-616, March 2021., 2021
ABSTRACT Skeletal homeostasis critically depends on the proper anabolic functioning of osteolineage cells. Proliferation and matrix synthesis are highly demanding in terms of biosynthesis and bioenergetics, but the nutritional requirements that support these processes in bone‐forming cells are not fully understood.
Steve Stegen, Claire‐Sophie Devignes, Sophie Torrekens, Riet Van Looveren, Peter Carmeliet, Geert Carmeliet   +5 more
wiley   +1 more source

A promising PET tracer candidate targeting α‐synuclein inclusions

, 2023
Clinical and Translational Medicine, Volume 13, Issue 9, September 2023.
Jie Xiang, Zhentao Zhang, Keqiang Ye
wiley   +1 more source

DOTATOC PET/CT imaging of a typical carcinoid tumor in a human ex-vivo perfused lung lobe

Quantitative Imaging in Medicine and Surgery, 2023
The use of Isolated lung perfusion (ILP), combined with medical imaging modalities such as positron emission tomography-computed tomography (PET/CT), provides real-time visualization of tumors in ventilated and perfused vital lung tissue. This experiment
A. Slama, B. Schaarschmidt, Ö. Okumuş, K. Herrmann, C. Aigner, S. Collaud, H. Hautzel   +6 more
semanticscholar   +1 more source

Neutrinoless Double Beta Decay, the Inverted Hierarchy and Precision Determination of theta(12) [PDF]

, 2011
Ruling out the inverted neutrino hierarchy with neutrinoless double beta decay experiments is possible if a limit on the effective mass below the minimal theoretically possible value is reached.
A. Giuliani,, Alexander Dueck, C. Nones, Kai Zuber, Werner Rodejohann, Y. Takeuchi   +5 more
core   +2 more sources

The Transparency of 12C for Protons [PDF]

, 2000
Existing cross-section data for 1p-shell knockout in the reaction 12C(e,e'p) - as obtained under different kinematic conditions - are shown to be mutually consistent, apart from a recent measurement performed in Mainz. New data have been collected at the
Frankfurt, L., Lapikas, L., Strikman, M., van der Steenhoven, G., Zhalov, M.   +4 more
core   +1 more source

Topical Review on "Beta-beams" [PDF]

, 2006
Neutrino physics is traversing an exciting period, after the important discovery that neutrinos are massive particles, that has implications from high-energy physics to cosmology.
Albright C, ALEPH, Angrik J (KATRIN Collaboration), Ardellier (the Double CHOOZ Collaboration), Autin B, Balantekin A B, Benedikt M Chancé A Lindroos M Payet J, Benedikt M Hancock S Lindroos M, Bernabeu J, Bernabeu J, Bernabeu J Burguet-Castell J Espinoza C, Bernabeu J Burguet-Castell J Espinoza C Lindroos M, Bouchez J, Campagne J E Maltoni M Mezzetto M Schwetz T, Chancé A Payet J, Cristina Volpe, Davidson S, De Gouvea A Jenkins J, Derbin A I, Donini A, Donini A Fernandez-Martinez, Efremenko Y, Elliott S R, Ereditato A Rubbia A, EURISOL Project, Fernandez-Martinez, Fogli G L, Giunti C Laveder M, GSI, Guglielmi A Mezzetto M Migliozzi P Terranova F, Haxton W C, Itow Y, Jachowicz N McLaughlin G C, Jachowicz N McLaughlin G C, Jung C K, Kneller J P McLaughlin G C Surman R, Kolbe E, Lindroos M, Lindroos M, Magistris M Silari M, Mezzetto M, Minakata H, Muto K, Pontecorvo B, Qian Y Z, Raffelt G G, Richter B, Rubbia A, Rubbia C, Rubbia C Ferrari A Kadii Y Vlachoudis V, Ruffert M, Singh S K Sajjad Athar M Ahmad S, Sortais P, Thomas A W, Vidyakin G S, Volpe C, Volpe C, Winter W, Zeller G P   +58 more
core   +3 more sources