Results 41 to 50 of about 951,017 (345)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Nuclear radii from first principles

Frontiers in Physics
With the combination of nuclear interactions from chiral effective field theory and various many-body techniques, one can perform systematically improvable ab initio calculations.
Takayuki Miyagi
doaj   +1 more source

Measurement of interaction between antiprotons

, 2015
One of the primary goals of nuclear physics is to understand the force between nucleons, which is a necessary step for understanding the structure of nuclei and how nuclei interact with each other.
STAR Collaboration
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Extensions of the Variational Method with an Explicit Energy Functional for Nuclear Matter with Spin-Orbit Force

Particles
Two extensions of the variational method with explicit energy functionals (EEFs) with respect to the spin-orbit force were performed. In this method, the energy per nucleon of nuclear matter is explicitly expressed as a functional of various two-body ...
Kento Kitanaka, Toshiya Osuka, Tetsu Sato, Hayate Ichikawa, Masatoshi Takano   +4 more
doaj   +1 more source

Hartree-Fock-Bogoliubov calculation of charge radii of Sn, Ba, Yb, and Pb isotopes [PDF]

, 2001
Charge radii of Sn, Ba, Yb, and Pb isotopes are calculated within Hartree-Fock-Bogoliubov theory with a Skyrme force and a density-dependent delta-force pairing. We investigate mean field effects of the pairing upon odd-even staggering of isotope shifts.
Audi, Aufmuth, Bonche, Chabanat, Dinger, Dobaczewski, Dutta, Eberz, Fayans, Fayans, Krömer, Raman, Regge, Reinhard, Reinhard, Ring, Sagawa, Sharma, Sharma, Shouichi Sakakihara, Tajima, Tajima, Talmi, Vautherin, Yasutoshi Tanaka   +24 more
core   +2 more sources

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Relation-based self-distillation method for 2D object detection

Scientific Reports
The challenge of enhancing the detection accuracy of widely adopted and stable object detectors while maintaining cost-effectiveness has long been a topic of significant interest and concern within the industry.
Bei Wang, Bing He, Chao Li, Xiaowei Shen, Xianyang Zhang   +4 more
doaj   +1 more source

Nuclear and gravitational energies in stars

, 2013
The force that governs the evolution of stars is gravity. Indeed this force drives star formation, imposes thermal and density gradients into stars at hydrostatic equilibrium and finally plays the key role in the last phases of their evolution.
Courvoisier, Thierry, Ekström, Sylvia, Meynet, Georges   +2 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source