Results 171 to 180 of about 2,214,209 (304)

MODELING THE PERFORMANCE OF HIGH BURNUP THORIA AND URANIA PWR FUEL

, 2002
Fuel performance models have been developed to assess the performance of ThO[subscript 2]-UO[subscript 2] fuels that can be operated to a high burnup up to 80-100MWd/kgHM in current and future Light Water Reactors (LWRs).
Kazimi, Mujid S., Long, Y., Meyer, J. E., Ballinger, Ronald G.   +3 more
core  

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Patch-Based convolutional neural networks for multiple microstructural features detection in FIB-SEM micrographs of irradiated nuclear fuel. [PDF]

Sci Rep
Uwaeze J, Tang Y, Mauseth TJ, Braverman V, Anderson MW, Wang Y, Xu F.   +6 more
europepmc   +1 more source

Insights into the Complexation Mechanism of a Promising Lipophilic PyTri Ligand for Actinide Partitioning from Spent Nuclear Fuel. [PDF]

Inorg Chem, 2022
Galluccio F, Macerata E, Weßling P, Adam C, Mossini E, Panzeri W, Mariani M, Mele A, Geist A, Panak PJ.   +9 more
europepmc   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Investigating the potential advantages of using thorium-based fuel as an advanced nuclear fuel in a typical boiling water reactor assembly (BWR). [PDF]

Sci Rep
Alnassar N, Galahom AA.
europepmc   +1 more source

Chemical and elemental mapping of spent nuclear fuel sections by soft X-ray spectromicroscopy. [PDF]

J Synchrotron Radiat, 2022
Ditter AS, Smiles DE, Lussier D, Altman AB, Bachhav M, He L, Mara MW, Degueldre C, Minasian SG, Shuh DK.   +9 more
europepmc   +1 more source

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

Advanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao, Jiatao Hao, Xiaohong Zhang, Meiting Long, Yujing Feng, Xiaoyue Liu, Xuejian Li, Shujuan Liu, Xin Guo, Xiaohui Lv   +9 more
wiley   +1 more source

Phosphate-Based Approaches for Dechlorination and Treatment of Salt Waste from Electrochemical Processing of Used Nuclear Fuel: A Perspective on Recent Work. [PDF]

ACS Omega
Evarts JS, Werth HS, Riley BJ, Carlson K, Simpson MF.   +4 more
europepmc   +1 more source

Short Alternative Route for Nuclear Fuel Reprocessing Based on Organic Phase Self-Splitting. [PDF]

Molecules, 2021
Durain J, Bourgeois D, Bertrand M, Meyer D.   +3 more
europepmc   +1 more source