Results 51 to 60 of about 1,717,092 (301)

Spanish Nuclear Safety Research under International Frameworks [PDF]

open access: yes, 2013
The Nuclear Safety research requires a wide international collaboration of several involved groups. In this sense this paper pretends to show several examples of the Nuclear Safety research under international frameworks that is being performed in ...
Miró Herrero, Rafael   +7 more
core   +1 more source

Radioactive Effluents from Nuclear Power Plants Annual Report [PDF]

open access: yes, 2010
This report describes radioactive effluents from commercial nuclear power plants (NPPs) in the United States. This information was reported by the licensees for radioactive discharges that occurred in 2007. The report provides information relevant to the
U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation.
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Features of fusion power measurements in next-generation magnetic plasma confinement experiments

open access: yesNuclear Fusion
Fusion power measurements provide one of the key benchmarks for any successful reactor-scale magnetic confinement fusion facility. In a deuterium–tritium fuel mix, neutrons carry about 4/5 of the produced fusion power outside the plasma volume. Thus, the
V. Krasilnikov   +19 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Process Instrumentation in Nuclear Power Plants [PDF]

open access: yes, 2015
Tema ovog završnog rada je "Procesna instrumentacija u nuklearnim elektranama". Na početku ovog rada bilo je potrebno istražiti sve moguće izvore kojima je tema procesna instrumentacija.
Krstanović, Matej
core   +1 more source

Nuclear Medicine Instrumentation [PDF]

open access: yesJournal of Nuclear Medicine Technology, 2013
J. Prekeges Burlington, Massachusetts: Jones and Bartlett, 2013, 376 pages, $105.95 This soft-cover textbook on nuclear instrumentation was written for an audience of nuclear medicine technology students, medical imaging technologists, nuclear medicine physicians, radiologists, medical ...
openaire   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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