Results 361 to 370 of about 1,162,025 (392)
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Biochemical and Biophysical Research Communications - BBRC, 2001
Human Scythe (also known as BAT3) has been implicated in the control of apoptosis and regulating heat shock protein (HSP) 70 activity. We have attempted to further characterize the role of human Scythe in HeLa cells by studying the cellular localization ...
Steve Manchen, A. Hubberstey
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Human Scythe (also known as BAT3) has been implicated in the control of apoptosis and regulating heat shock protein (HSP) 70 activity. We have attempted to further characterize the role of human Scythe in HeLa cells by studying the cellular localization ...
Steve Manchen, A. Hubberstey
semanticscholar +1 more source
Journal of Molecular Biology, 2007
The influenza A genome consists of eight single-stranded RNA molecules, each associated with an oligomeric core of the structural protein, nucleoprotein, to form a distinct viral ribonucleoprotein (vRNP) complex. vRNPs are the entities responsible for the transcription and replication of the influenza viral RNAs in the nuclei of host cells.
Lindsay L. Weaver +2 more
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The influenza A genome consists of eight single-stranded RNA molecules, each associated with an oligomeric core of the structural protein, nucleoprotein, to form a distinct viral ribonucleoprotein (vRNP) complex. vRNPs are the entities responsible for the transcription and replication of the influenza viral RNAs in the nuclei of host cells.
Lindsay L. Weaver +2 more
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The Immunoreactive Region in a Novel Autoantigen Contains a Nuclear Localization Sequence
Clinical Immunology and Immunopathology, 1994Antibodies in the serum of patients with autoimmune diseases have been used to identify human autoantigens. Because autoantibodies often recognize active sites within corresponding protein antigens, autoantibodies have facilitated the functional characterization of these polypeptides.
Daniel Bloch +3 more
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Antibodies against the SV40 large T antigen nuclear localization sequence
Archives of Biochemistry and Biophysics, 1991Transport of large proteins into the nucleus requires both a nuclear localization signal (NLS) and exposure of that signal to components of the transport machinery. In this report, polyclonal and monoclonal antibodies were generated against the NLS of SV40 large T antigen.
Barbara Wolff +3 more
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The Fluorinated and Chlorinated Nuclear Localization Sequence of the SV 40 T Antigen
Chemical Biology & Drug Design, 2008Nuclear uptake of the simian virus (SV) 40 T antigen is triggered by a specific nuclear localization sequence. However, such a nuclear localization sequence is only poorly taken up by the cytoplasm of cells when administered to the culture medium.
Alexander Sturzu, Stefan Heckl
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Identification of sequence determinants of human nuclear dUTPase isoform localization
Experimental Cell Research, 2003dUTP nucleotidohydrolase (dUTPase) catalyzes the hydrolysis of dUTP to dUMP and pyrophosphate and is the central regulator of cellular dUTP pools. Nuclear (DUT-N) and mitochondrial (DUT-M) isoforms of the protein have been identified in humans and arise from the same gene by the alternative use of 5' exons.
Tinkelenberg, Beverly A +3 more
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A novel transfecting peptide comprising a tetrameric nuclear localization sequence
Journal of Molecular Medicine, 2003The transport of exogenous DNA into the nucleus of eukaryotic cells is a prerequisite for successful gene delivery. To favor nuclear transport we synthesized a tetramer of the nuclear localization signal (NLS) of the SV40 large T-antigen as a novel nonviral gene delivery vector.
James Lausier +6 more
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Identification of a nuclear localization sequence in the polyomavirus capsid protein VP2
Virology, 1992A nuclear localization signal (NLS) has been identified in the C-terminal (Glu307-Glu-Asp-Gly-Pro-Gln-Lys-Lys-Lys-Arg-Arg-Leu318) amino acid sequence of the polyomavirus minor capsid protein VP2. The importance of this amino acid sequence for nuclear transport of newly synthesized VP2 was demonstrated by a genetic "subtractive" study using the ...
John N. Brady +3 more
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Characterization of a nuclear localization sequence in the polyomavirus capsid protein VP1
Virology, 1991Expression of VP1-beta-galactosidase fusion proteins in the yeast Saccharomyces cerevisiae was used to identify a domain of the polyomavirus VP1 capsid protein which targets this protein to the nucleus. Fusion of the first 17 amino acids of VP1 to beta-galactosidase was sufficient for nuclear localization, whereas fusion of the first 12 amino acids ...
Robert L. Garcea, Robert B. Moreland
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14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4.
Biochemistry, 2005The 14-3-3 proteins are a family of regulatory signaling molecules that interact with other proteins in a phosphorylation-dependent manner. 14-3-3 proteins are thought to play a direct role in the regulation of subcellular localization of FoxO forkhead ...
V. Obsilova +7 more
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