Results 31 to 40 of about 3,649,784 (288)

Hyperpolarized singlet NMR on a small animal imaging system [PDF]

, 2012
Nuclear spin hyperpolarization makes a significant advance toward overcoming the sensitivity limitations of in vivo magnetic resonance imaging, particularly in the case of low-gamma nuclei.
Brown, Richard C. D., Ardenkjær-Larsen, Jan Henrik, Tayler, Michael C.D., Levitt, Malcolm H., Tayler, Michael C. D., Laustsen, Christoffer, Brown, Lynda J., Ardenkjaer-Larsen, Jan H., Pileio, Giuseppe, Brown, Richard C.D.   +9 more
core   +1 more source

Structure Confirmation of Three New Psychoactive Substances and Qualitative Identification of Unknown Substances

Fayixue Zazhi
ObjectiveTo establish the structural confirmation methods of three suspected new psychoactive substances （NPSs）, and explore a more general qualitative testing method.MethodsInfrared absorption spectroscopy （IR）, gas chromatography-mass spectrometry （GC ...
NIE Zong-yang, HU Wei, LI Ling-yu, ZHANG Qing-bo, HUANG Xin, LI Bo   +5 more
doaj   +1 more source

Synthesis, spectral, antimicrobial, and antifertility studies of tetraaza macrocyclic complexes of tin(II)

Main Group Metal Chemistry, 2013
A novel family of tetraazamacrocyclic complexes of Sn(II) has been synthesized by template condensation using 1,9-diaminononane with different dicarboxylic acids (malonic, succinic, glutaric, and adipic).
Bansal Nidhi, Dave Saurabh
doaj   +1 more source

Synthesis and Theoretical Calculations of Benzoic Acid-Based New Mono Azo Dye

Süleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2022
This study describes the synthesis, characterization and theoretical calculation of 3,5-dihydroxy-2-(naphthalen-2-yldiazenyl) benzoic acid. The synthesized compound was obtained through efficient synthetic route using 2-Naphthylamine and 3,5 ...
Mehmet Ulutürk, Çiğdem Karabacak Atay
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Structure and ion transport properties of organic ionic compounds revealed by NMR

Magnetic Resonance Letters
Organic ionic plastic crystals (OIPCs) are emerging as an important material family for solid-state electrolytes and many other applications. They have significant advantages over conventional electrolyte materials, such as high ionic conductivity, non ...
Haijin Zhu
doaj   +1 more source

High-Resolution Nanoscale Solid-State Nuclear Magnetic Resonance Spectroscopy

Physical Review X, 2018
We present a new method for high-resolution nanoscale magnetic resonance imaging (nano-MRI) that combines the high spin sensitivity of nanowire-based magnetic resonance detection with high-spectral-resolution nuclear magnetic resonance (NMR) spectroscopy.
William Rose, Holger Haas, Angela Q. Chen, Nari Jeon, Lincoln J. Lauhon, David G. Cory, Raffi Budakian   +6 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Pushing nuclear magnetic resonance sensitivity limits with microfluidics and photo-chemically induced dynamic nuclear polarization

Nature Communications, 2018
Nuclear magnetic resonance (NMR) spectroscopy is a powerful technique with an inherently low sensitivity. Here, the authors present a combination of microcoils with photo-chemically induced dynamic nuclear polarization to boost NMR sensitivity down to ...
Miguel Mompeán, Rosa M. Sánchez-Donoso, Antonio de la Hoz, Vittorio Saggiomo, Aldrik H. Velders, M. Victoria Gomez   +5 more
doaj   +1 more source