Results 41 to 50 of about 350,990 (301)

Effect of fertilizers and growth stimulants on the content of coumarin and its derivatives in the vegetative mass of melilot [PDF]

open access: yesBrazilian Journal of Biology
The paper presents the results of determining the content of coumarin and its derivatives in the melilot using nuclear magnetic resonance spectroscopy, including the study of the effect of fertilizers on the quantitative content of coumarin and its ...
M. N. Suraganov   +4 more
doaj   +1 more source

Applications of Solid-State Nuclear Magnetic Resonance Spectroscopy in Methanol-to-Olefins Reaction

open access: yesChinese Journal of Magnetic Resonance, 2021
Methanol-to-olefins (MTO) is a prevalent industrial process for producing light olefins from the non-petroleum route. Molecular sieves are core catalysts for MTO owing to their unique pore structure and tunable acidity.
Shu-shu GAO   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Practical Applications of NMR to Solve Real-World Problems

open access: yesMolecules, 2021
Nuclear magnetic resonance spectroscopy (NMR) is known to be a powerful technique for the characterization of small molecules and structural and dynamics studies of biomolecules [...]
Robert G. Brinson
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

New Insights into Nuclear Magnetic Resonance (NMR) Spectroscopy

open access: yesMolecules
NMR spectroscopy is playing an increasing role in chemistry, biology, material sciences and related disciplines [...]
Ioannis P. Gerothanassis, Teobald Kupka
doaj   +1 more source

Solid-State NMR Studies on the Surface Structure and Properties of Oxide Nanomaterials

open access: yesChinese Journal of Magnetic Resonance, 2021
Many applications of oxide nanomaterials depend on their surface structure and properties. Solid-state nuclear magnetic resonance (NMR) spectroscopy has been used to obtain such key information in related studies.
Xi-feng XIA   +7 more
doaj   +1 more source

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