Results 151 to 160 of about 199,440 (313)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Signatures of quark gluon plasma formation in high-energy heavy ion collisions : a critical review

, 2005
Ultra-relativistic heavy ion collisions offer the unique opportunity to probe highly excited dense nuclear matter under controlled laboratory conditions. The compelling driving force for such studies is the expectation that an entirely new form of matter
Greiner, Walter, Stöcker, Horst, Bass, Steffen A., Gyulassy, Miklos   +3 more
core  

Nuclear Matter Equation of State in the Brueckner–Hartree–Fock Approach and Standard Skyrme Energy Density Functionals

Universe
The equation of state of asymmetric nuclear matter as well as the neutron and proton effective masses and their partial-wave and spin–isospin decomposition are analyzed within the Brueckner–Hartree–Fock approach.
Isaac Vidaña, Jérôme Margueron, Hans-Josef Schulze   +2 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Introduction to Applied Nuclear Physics

, 2003
This course concentrates on the basic concepts of nuclear physics with emphasis on nuclear structure and radiation interactions with matter. Included: elementary quantum theory; nuclear forces; shell structure of the nucleus; alpha, beta, and gamma ...
Molvig, Kim
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Supplement no. 1 to the Safety evaluation report by the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission in the matter of Power Authority of the State of New York, Greene County Nuclear Power Plant, Docket no. 50-549.

, 1978
"September 5, 1978."Cover title: Safety evaluation report related to construction of Greene County Nuclear Power Plant, Power Authority of the State of New York. Supplement no. 1."NUREG-0283, Supplement No.
U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation.
core  

The coexistence curve of finite charged nuclear matter [PDF]

, 2001
The multifragmentation data of the ISiS Collaboration and the EOS Collaboration are examined. Fisher's droplet formalism, modified to account for Coulomb energy, is used to determine the critical exponents {tau} and {sigma}, the surface energy ...
Hirsch, A. S., Justice, M., Lindenstruth, V., Keane, D., Tincknell, M., Wieman, H. H., Chacon, A.D., Breuer, H., Hirsch, A.S., Shao, Y., Symons, T.J.M., Moretto, L. G., Viola, V. E., Warren, P., Lisa, M.A., Rai, G., Costa, S., Gilkes, M. L., Muller, W. F. J., Hjort, E.L., Brady, F.P., Lisa, M. A., Korteling, R. G., Viola, V.E., Sann, H., Matis, H.S., Korteling, R.G., Gilkes, M.L., Olson, D.L., Caccia, Z., Bieser, F., Pienkowski, L., Russo, G. V., McMahan, M., Phair, L., Elliott, J. B., Romero, J. L., Choi, Y., Wienold, T., Wozniak, G.J., Partlan, M.D., Scott, A., Cebra, D. A., Porile, N. T., Romero, J.L., Srivastava, B.K., Wieman, H.H., Romanski, J., Chance, J.L., Kintner, J. C., Wozniak, G. J., McParland, C., Rasmussen, J., Partlan, M. D., Tuve, C., Matis, H. S., Chance, J. L., Symons, T. J. M., Insolia, A., Russo, G.V., Kwiatkowski, K., Ruangma, A., Brady, F. P., Potenza, R., Wang, S., Hjort, E. L., Srivastava, B. K., Scharenberg, R.P., Yennello, S. J., Lefort, T., Albergo, S., Chacon, A. D., Hauger, J. A., Moretto, L.G., Scharenberg, R. P., Elliott, J.B., Kintner, J.C., Ritter, H.G., Hauger, J.A., Ritter, H. G., Olson, D. L., Beaulieu, L., Yennello, S.J., Cebra, D.A., Muller, W.F.J., Wolf, K., Porile, N.T.   +86 more
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source