Results 131 to 140 of about 4,987,259 (403)
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Research practice development for nuclear medicine technologists: an innovative experience [PDF]
, 2014 Introduction - European nuclear medicine technologist’s education is delivered by Higher Education Institutions and students obtain a grade of Bachelor of Sciences (BSc), during which they are initiated to research during their studies. Once BSc nuclear
Allenbach, G. +8 more
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Current possibilities for developing nuclear medicine in Russia
Патология кровообращения и кардиохирургия, 2018 Focus in this article is placed on the areas of application of nuclear medicine methods, the existing structure of the nuclear medicine market in the world and the scope of implementation of these methods into practice of the Russian health care.
V. D. Markova, A. N. Pukhalskiy
doaj +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Toward optimal X-ray flux utilization in breast CT [PDF]
, 2011 A realistic computer-simulation of a breast computed tomography (CT) system and subject is constructed. The model is used to investigate the optimal number of views for the scan given a fixed total X-ray fluence.
Hansen, Per Christian +4 more
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Tako-Tsubo Syndrome: Atypical Nuclear Medicine Findings
World Journal of Nuclear Medicine, 2012 The Tako-Tsubo syndrome is a reversible form of an acute stress-related cardiomyopathy that was reported during the last decade. It typically presents with a constellation of symptoms, electrocardiographic changes, and elevated cardiac enzyme levels ...
Lázaro Cabrera Rodríguez +3 more
doaj +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Rare earth elements in nuclear medicine [PDF]
Саратовский научно-медицинский журнал, 2014 The review focuses on the key applications of stable and radioactive isotopes of rare earth elements in the technology of nuclear medicine, radionuclide diagnostics and therapy, as well as magnetic resonance imaging and binary radiotherapy technologies.
Kodina G.E., Kulakov V.N., Sheino I.N.
doaj
THE AMERICAN JOURNAL OF ROENTGENOLOGY RADIUM THERAPY AND NUCLEAR MEDICINE [PDF]
, 1966 openalex +1 more source