Results 171 to 180 of about 4,987,259 (403)
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
A la caça del fotó. Detectors de partícules en imatge mèdica [PDF]
Hunting the Photon. Particle Detectors in Medical Imaging.Nuclear and particle physicists have always worked hard to develop particle detectors to measure the fundamental properties of matter.
Carlos Lacasta
core +1 more source
This work presents a new possibility of registration of ionizing radiation by the flowing gaseous radiochemical method (FGRM). The specified method uses the property of some solid crystalline lattice materials for a free emission of radioactive isotopes ...
A.S. Iljinov+13 more
core +1 more source
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo+11 more
wiley +1 more source
Essential nuclear medicine physics
N. C. Purandare, V. Rangarajan
doaj +1 more source
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim+11 more
wiley +1 more source
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley +1 more source