Results 291 to 300 of about 4,987,259 (403)
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang+6 more
wiley +1 more source
IDAC-Dose 2.2, an internal dosimetry software for diagnostic nuclear medicine based on the latest ICRP adult and paediatric reference computational phantoms. [PDF]
Andersson M, Eckerman K, Mattsson S.
europepmc +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Development of LAT1-Selective Nuclear Medicine Therapeutics Using Astatine-211. [PDF]
Kaneda-Nakashima K+13 more
europepmc +1 more source
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav+5 more
wiley +1 more source
Nuclear Medicine and Molecular Imaging in Urothelial Cancer: Current Status and Future Directions. [PDF]
McDonald S, Keane KG, Gauci R, Hayne D.
europepmc +1 more source