Results 151 to 160 of about 651,872 (305)

Declining Discount Rates: Evidence from the UK [PDF]

open access: yes
We estimate schedules of declining discount rates for cost benefit analysis in the UK. We highlight the importance of model selection for this task and hence for the evaluation of long-term investments, namely climate change prevention and nuclear build ...
B. Groom   +3 more
core  

Temporal Modeling of Amyloid and Tau Trajectories in Alzheimer's Disease Using PET and Plasma Biomarkers

open access: yesAnnals of Neurology, EarlyView.
Objective This study aimed to compare positron emission tomography (PET) and plasma‐based temporal modeling of amyloid and tau biomarkers in Alzheimer's disease. Methods Longitudinal amyloid PET (n = 1,097, mean age ± SD = 72.5 ± 7.38 year, 51.4% male), 18F‐flortaucipir tau‐PET (n = 230, 74.3 ± 7.18 year, 52.2% female), and Fujirebio Lumipulse plasma p‐
Christopher A. Brown   +14 more
wiley   +1 more source

Mesoporous Silica Nanoparticles With Customized Drug Ratio/Loading for Effective Treatment of Gemcitabine‐Resistant Pancreatic Tumors

open access: yesAdvanced NanoBiomed Research, EarlyView.
Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq   +5 more
wiley   +1 more source

Social Discounting Under Uncertainty: A cross-country comparison [PDF]

open access: yes
Recent research suggests that social cost-benefit analysis should be con- ducted with a declining discount rate. For instance, Newell and Pizer [23] show that the U.S.
Cameron Hepburn   +3 more
core  

Embedding Chemistry and Pharmacy Into Sustainability

open access: yesAngewandte Chemie International Edition, EarlyView.
Chemistry and pharmacy provide products and processes that are indispensable for our high living standard. To understand their relationship with sustainability is important to allow them to contribute to sustainability in a sustainable manner. An integrated overview of green, circular, and sustainable chemistry and pharmacy is given and how they have t
Klaus Kümmerer
wiley   +1 more source

Ending nuclear weapons, before they end us. [PDF]

open access: yesBMJ Mil Health
Zielinski C   +1 more
europepmc   +3 more sources

DEVOTED ACTOR VERSUS RATIONAL ACTOR MODELS FOR UNDERSTANDING WORLD CONFLICT Presented To The National Security Council At The White House, September 14, 2006 [PDF]

open access: yes
Ever since the end of the Second World War, Rational Actor models have dominated strategic thinking at all levels of government policy and military planning.
Scott Atran
core  

Potassium Migration of Chestnut Shell Ashes Under Oxidizing Atmosphere and Its Modification Mechanism by Additives

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Biomass energy plays a critical role in alleviating environmental pressures. However, its relatively high content of alkali metals (especially for potassium) would cause ash‐related issues during combustion. To mitigate these issues, the potassium migration behaviors during chestnut shell (CS) conversion and the modification mechanisms of ...
Meijie Zhou   +6 more
wiley   +1 more source

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

open access: yesAnimal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad   +7 more
wiley   +1 more source

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