Results 81 to 90 of about 650,518 (304)

Security in northeast Asia: structuring a settlement [PDF]

open access: yes, 2019
A potential pathway exists for a Northeast Asian settlement where the Koreas, the United States, China, and Japan can each live within the status quo. Sustaining a settlement will require reining in foreign policy hawks reluctant to allow the Democratic
Shifrinson, Joshua
core  

Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression

open access: yesAdvanced Science, EarlyView.
This study uncovers a new oncogenic mechanism in melanoma. The transcription factor PATZ1 competes with the architectural protein CTCF for DNA binding, thereby disrupting a specific chromatin loop and silencing the tumor suppressor ZBTB20. This event unleashes the pro‐tumorigenic PMEPA1‐p38‐STAT1 signaling axis, promoting cancer progression.
Chaowei Deng   +8 more
wiley   +1 more source

Japan Should Scrutinise the Credibility of the US Nuclear Umbrella: An Interview with Shigeru Ishiba

open access: yesJournal for Peace and Nuclear Disarmament, 2018
Shigeru Ishiba is a heavyweight in Japan’s Liberal Democratic Party and served as Defence Minister from 2007 to 2008. In this interview, he shares his views on the role of nuclear weapons in US–Japan alliance and Japan’s security policy.
Fumihiko Yoshida
doaj   +1 more source

Perspectives of Nuclear Physics in Europe: NuPECC Long Range Plan 2010 [PDF]

open access: yes, 2010
The goal of this European Science Foundation Forward Look into the future of Nuclear Physics is to bring together the entire Nuclear Physics community in Europe to formulate a coherent plan of the best way to develop the field in the coming decade and ...
Bracco, A.   +9 more
core  

The Changing Perspectives of U.S and Japanese Nuclear Energy Policies in the Aftermath of the Fukushima Daiichi Disaster [PDF]

open access: yes, 2013
This Comment examines the aftermath of the Fukushima Daiichi nuclear disaster, and its impact on American and Japanese nuclear energy policies. The second section of this Comment provides a brief history of the United States’ nuclear energy policy ...
Dorfman, Daniel A.
core   +2 more sources

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

open access: yesAdvanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu   +15 more
wiley   +1 more source

No First Use and Credible Deterrence

open access: yesJournal for Peace and Nuclear Disarmament, 2018
Despite progress in reducing the number of nuclear weapons in the largest arsenals, a number of states are now looking to increase their reliance on nuclear weapons not only for deterrence, but also for coercion or war fighting.
Steve Fetter, Jon Wolfsthal
doaj   +1 more source

Iranian foreign policy under Rouhani [PDF]

open access: yes
In this Lowy Institute Analysis Rodger Shanahan examines changes in Iranian foreign policy under President Rouhani. He argues that while the Iranian President has changed the tone of Iranian foreign policy, changing the substance will prove much more ...
Rodger Shanahan
core  

Nuclear Waste and Native America: The MRS Siting Exercise [PDF]

open access: yes, 1998
Drs. Gowda & Easterling provide cross-cultural perspectives on issues of risk perception, equity and policy as they affect nuclear waste storage on Native American ...
Easterling, Doug, Gowda, M. V. Rajeev
core   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy   +8 more
wiley   +1 more source

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