Results 41 to 50 of about 6,592,670 (293)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Emergency preparedness and emergency training & drill of Hamaoka Nuclear Power Station

Nihon Kikai Gakkai ronbunshu, 2018
Hamaoka Nuclear Power Station (NPS) has always embraced the most up-to-date knowledge in its effort to enhance safety. Following the accident at TEPCO’s Fukushima Daiichi Nuclear Power Station, we have been implementing voluntary countermeasures for ...
Akira GOTO, Hajime FUKUMOTO, Nobuo SHIMIZU, Keisuke TOKUMURA, Junya SUZUKI, Katsumi YAMADA   +5 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Multiobjective Mixed Integer Nonlinear Model to Plan the Schedule for the Final Disposal of the Spent Nuclear Fuel in Finland

Mathematics, 2020
The safe disposal of the spent nuclear fuel is the important part of the nuclear power production. In this paper, we model the geological disposal in Finland covering objectives related to the interim storage, the encapsulation facility, the disposal ...
Outi Montonen, Ville-Pekka Eronen, Timo Ranta, Jani A. S. Huttunen, Marko M. Mäkelä   +4 more
doaj   +1 more source

Safety and security [PDF]

, 2012
This paper is the sixth in a series of 8 that make up the evidence base for SDC report 'The role of nuclear power in a low carbon economy'.The document covers accident risk in plants (including a historical review of accidents), threats from design ...
AMEC NNC Limited, Large & Associates, Sustainable Development Commission   +2 more
core   +2 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

A central facility concept for nuclear microreactor maintenance and fuel cycle management

Nuclear Engineering and Technology
Commercial deployment of nuclear microreactors presents an opportunity for the industry to rethink its approach to manufacturing, siting, operation and maintenance, and fuel cycle management as certain principles used in grid-scale nuclear projects are ...
Faris Fakhry, Jacopo Buongiorno, Steve Rhyne, Benjamin Cross, Paul Roege, Bruce Landrey   +5 more
doaj   +1 more source

Circular polarization measurement of γ-rays emitted from 32S(n,γ)33S reaction with polarized neutrons [PDF]

EPJ Web of Conferences
We aim to measure circular polarization of γ-rays emitted from neutron capture reactions with a pulsed neutron source for nuclear data and nuclear physics studies. A γ-ray polarimeter was developed to measure the circular polarization. One of performance
Endo Shunsuke, Fujioka Hiroyuki, Ide Ikuo, Inuma Masataka, Iwamoto Nobuyuki, Iwamoto Osamu, Kameda Kento, Kawamura Shiori, Kimura Atsushi, Kitaguchi Masaaki, Kobayashi Ryujyu, Nakamura Shoji, Oku Takayuki, Okudaira Takuya, Okuizumi Mao, Rovira Gerard, Shima Tatsushi, Shimizu Hirohiko, Takada Shusuke, Takahashi Shingo, Yoshikawa Hiromoto, Yoshioka Tamaki   +21 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source