Results 111 to 120 of about 8,240,057 (298)

Development and Verification of CUPID-MSR Using the de Vahl Davis Natural-Convection Benchmark

open access: yesEnergies
This study provides the first systematic verification of the CUPID-MSR thermal–hydraulic code for molten-salt reactor applications, incorporating temperature-dependent thermophysical properties of two chloride-based molten salts, KCl–UCl3 and NaCl–MgCl2 ...
Rafał Stoga   +2 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Coastal Environment and a Nuclear Power Plant

open access: yesCoastal Engineering 1976, 1976
Regulatory requirements and social constraints make it necessary to evaluate the environmental effects of a project and to incorporate into the design features to minimize adverse environmental impacts. This paper presents a case history of efforts to meet these requirements for a coastal power plant in southern California, Southern California Edison ...
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Safety in nuclear power plants in India

open access: yesIndian Journal of Occupational and Environmental Medicine, 2008
Safety in nuclear power plants (NPPs) in India is a very important topic and it is necessary to dissipate correct information to all the readers and the public at large. In this article, I have briefly described how the safety in our NPPs is maintained. Safety is accorded overriding priority in all the activities.
openaire   +3 more sources

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Troublesome Investment. The Belarusian Nuclear Power Plant in Astravyets. OSW Studies 74, July 2018 [PDF]

open access: yes, 2018
When Belarus embarked on the construction of its first nuclear power plant in Astravyets in 2012, the official objective was to significantly reduce the share played by imported Russian gas in the country’s electricity production. However, the Belarusian
Kardaś, Szymon   +2 more
core  

Flow Heat Transfer Characteristics and Dynamic Response of Once-Through Cooling Water System in Nuclear Power Plants Under Complex Operating Conditions

open access: yesEnergies
As a critical component of nuclear power units, the direct cooling water system plays a key role in overall performance. To maintain economic efficiency, it is necessary to adjust the circulating water flow rate as conditions change.
Qian Huang   +5 more
doaj   +1 more source

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