Results 321 to 330 of about 8,612,670 (377)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

LEM-Domain-Containing Inner Nuclear Membrane Proteins: Emerging Regulators of Intranuclear Signaling. [PDF]

Int J Mol Sci
Lee B, Lee H, Shim J.
europepmc   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, In collaboration with the Consensus Expert Panel (CEP) members   +19 more
wiley   +1 more source

Drosophila Keap1 Proteins Assemble Nuclear Condensates in Response to Oxidative Stress. [PDF]

Antioxidants (Basel)
Ji G, Cross B, Killmer T, Enders B, Neidviecky E, Huber H, Lynch G, Deng H.   +7 more
europepmc   +1 more source

Old dogs with new tricks: intra-axonal translation of nuclear proteins.

Neural Regen Res, 2015
Twiss JL, Merianda TT.
europepmc   +1 more source

Reviewer #2 (Public review): Nuclear and cytosolic J-domain proteins provide synergistic control of Hsf1 at distinct phases of the heat shock response

Carmen Ruger-Herreros, Lucia Svoboda, Gurranna Male, Aseem Shrivastava, Markus Höpfler, Katharina Jetzinger, Jiri Koubek, Günter Kramer, Fabian den Brave, Axel Mogk, David S Gross, Bernd Bukau   +11 more
openalex   +1 more source

An elevated level of the mRNA exporter Mex67-Mtr2 in nuclear mRNPs impairs nuclear mRNA export. [PDF]

Nucleic Acids Res
Stefanyshena N, Sträßer K.
europepmc   +1 more source

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Extraction of Nuclear Proteins

Methods in molecular biology, 2006
The integrity of a subcellular proteome such as the nucleus, is largely dependent on purification of the isolated compartment away from other cellular contaminants. The separation of high-purity nuclei from plants is a difficult task. However, successful purification has been achieved through a series of fractionation processes.
S. Komatsu
openaire   +3 more sources

Nuclear protein localization

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1991
L'article est une revue generale concernant le transport, apres synthese cytoplasmique, des proteines nucleaires dans le noyau a travers la membrane nucleaire. Les techniques d'etude sont presentees (techniques in vivo sur cellules, in vitro sur noyaux artificiels ou noyaux naturels reconstitues, approche genetique).
Garcia-Bustos, J., Heitman, J., Hall, M. N.   +2 more
openaire   +3 more sources

Nuclear protein kinases

Molecular and Cellular Biochemistry, 1984
Nuclear protein kinases include enzymes that transfer the gamma-phosphate of ATP to serine, threonine, lysine or histidine in proteins. Nuclear kinases with a preference for basic proteins are known as histone kinases; those preferring acidic protein substrates are casein kinases.
H R, Matthews, V D, Huebner
openaire   +2 more sources