Results 141 to 150 of about 7,292,547 (369)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Advances in nuclear reaction calculations by incorporating information from nuclear mean-field theories

EPJ Web of Conferences, 2017
Mean-field model calculations for nuclear structure theories are combined with the statistical Hauser-Feshbach code in order to improve predictive capabilities of nuclear reaction for experimentally unknown cross sections.
Kawano Toshihiko
doaj   +1 more source

On the Nuclear Photo-Reaction, II [PDF]

, 1955
S. Fujii, S. Takagi
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Symplectic coherent-state bases in the OCM calculations of nuclear cluster systems

Physical Sciences and Technology, 2020
In order to solve many-body states in a wide energy region including continuum states, it is strongly desired to develop a useful method. In nuclear cluster systems [1, 2,], we must treat both bound and unbound states simultaneously.
K. Kato, V. S. Vasilevsky, N. Takibayev
doaj  

Measurement and theoretical analysis of cross sections nuclear reaction (n, p), (n, α), (n, 2n) on isotopes of dysprosium, erbium and ytterbium [PDF]

Ядерна фізика та енергетика, 2012
Cross section of the nuclear reactions (n, p), (n, α), (n, 2n) were measured on isotopes of dysprosium, erbium and ytterbium at the neutron energies 14.6 ± 0.2 MeV.
O. M. Gorbachenko, N. R. Dzysiuk, A. O. Kadenko, I. M. Kadenko, V. A. Plujko, G. I. Primenko   +5 more
doaj  

Kinetic studies on the metabolism of foreign organic compounds. 6. Reactions of some nuclear-substituted benzoic acids, benzamides and toluenes in the rabbit [PDF]

, 1955
H. G. Bray, Brenda G. Humphris, W. V. Thorpe, Kenneth L. White, Patricia Burke Wood   +4 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

A simple organized approach for balancing nuclear equation

Revista Brasileira de Ensino de Física
This paper reports on the development of a simple organized approach for balancing a given nuclear equation in which all the reactants and products appear explicitly.
Pramode Ranjan Bhattacharjee
doaj   +1 more source