Results 141 to 150 of about 712,904 (293)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Uncovering Special Nuclear Materials by Low-energy Nuclear Reaction Imaging. [PDF]

Sci Rep, 2016
Rose PB, Erickson AS, Mayer M, Nattress J, Jovanovic I.   +4 more
europepmc   +1 more source

Efficient time-series forecasting of nuclear reactions using swarm intelligence algorithms

, 2022
Hala Shaker Mehdy, Nariman Jabbar Qasim, Haider Hadi Abbas, Israa Al Barazanchi, Hassan Muwafaq Gheni   +4 more
openalex   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

First sub-MeV nuclear reaction measurements in a heavy-ion storage ring. [PDF]

Eur Phys J A Hadron Nucl
Marsh JJ, Bruno CG, Davinson T, Woods PJ, Andelkovic Z, Barbieri L, Bemmerer D, Biniskos A, Boudefla D, Corvisiero P, Csedreki L, Dellmann SF, Fedotova S, Friere-Fernández D, Forstner O, Glorius J, Gumberidze A, Hanu EO, Herfurth F, Hillenbrand PM, Hubbard N, Kalinin A, Krantz C, Lestinsky M, Litvinov Y, Masha E, Menz EB, Müller DA, Nociforo C, Petridis N, Robb D, Rooney A, Sanjari MS, Sidhu RS, Skowronski J, Spillman U, Stöhlker T, Vorobyev G, Wang Y, Wilsenach H, Yamaguchi T.   +40 more
europepmc   +1 more source

Exclusive measurements of nuclear breakup reactions of¹⁷Ne [PDF]

, 2014
F. Wamers, J. Marganiec, F. Aksouh, Yu. Aksyutina, H. Álvarez-Pol, T. Aumann, S. Beceiro-Novo, C. A. Bertulani, K. Boretzky, M. J. G. Borge, M. Chartier, A. Chatillon, L.V. Chulkov, D. Cortina‐Gil, И. А. Егорова, H. Emling, O. Ershova, C. Forssén, L. M. Fraile, H. O. U. Fynbo, D. Galaviz, H. Geißel, L. V. Grigorenko, M. Heil, D. H. H. Hoffmann, J. Hoffmann, H. Johansson, B. Jonson, C. Karagiannis, M. Karakoç, O.A. Kiselev, J. V. Kratz, R. Kulessa, N. Kurz, Christoph Langer, M. Lantz, K.E. Larsson, T. Le Bleis, R. C. Lemmon, Yu. A. Litvinov, K. Mahata, C. Müntz, T. Nilsson, C. Nociforo, G. Nyman, W. Ott, V. Panin, Yu. L. Parfenova, S. Paschalis, Á. Perea, R. Plag, R. Reifarth, A. Richter, C. Rodríguez–Tajes, D. Rossi, K. Riisager, D. Savran, G. Schrieder, N.B. Shul’gina, H. Simon, J. Stroth, K. Sümmerer, J. T. Taylor, O. Tengblad, E. Tengborn, H. Weick, K. Wimmer, M.V. Zhukov   +67 more
openalex   +1 more source

Nuclear Reactions [PDF]

Nature, 1967
openaire   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Hybrid Gene Selection Algorithm for Cancer Classification Using Nuclear Reaction Optimization (NRO). [PDF]

Curr Issues Mol Biol
Alkamli S, Alshamlan H.
europepmc   +1 more source