Results 151 to 160 of about 7,324,154 (387)
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Determination of plasma screening effects for thermonuclear reactions in laser-generated plasmas
, 2017 Due to screening effects, nuclear reactions in astrophysical plasmas may behave differently than in the laboratory. The possibility to determine the magnitude of these screening effects in colliding laser-generated plasmas is investigated theoretically ...
Pálffy, Adriana, Wu, Yuanbin
core +1 more source
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Molecular Oncology, EarlyView.VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park +6 more
wiley +1 more source
Author Correction: Localized nuclear reaction breaks boron drug capsules loaded with immune adjuvants for cancer immunotherapy. [PDF]
Nat Commun, 2023 Shi Y +11 more
europepmc +1 more source
Chiral symmetry and strangeness at SIS energies
, 2003 In this talk we review the consequences of the chiral SU(3) symmetry for strangeness propagation in nuclear matter. Objects of crucial importance are the meson-baryon scattering amplitudes obtained within the chiral coupled-channel effective field theory.
Aichelin +45 more
core +2 more sources
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
C12+16O molecular resonances at deep sub-barrier energy
Physics Letters B, 2020 The existence of C12+16O molecular resonances at sub-barrier energy has been a significant problem in nuclear astrophysics because they strongly affect the C12+16O fusion reaction rate in type Ia supernovae and heavy stars.
Yasutaka Taniguchi, Masaaki Kimura
doaj
Nuclear reaction rates and the primordial nucleosynthesis [PDF]
Rom.J.Phys.57:1317-1327,2012, 2011 The theoretical predictions of the primordial abundances of elements in the big-bang nucleosynthesis (BBN) are dominated by uncertainties in the input nuclear reaction rates. We investigate the effect of modifying these reaction rates on light element abundance yields in BBN by replacing the thirty-five reaction rates out of the existing eighty-eight ...
arxiv
Performance Improvements for Nuclear Reaction Network Integration
, 2014 Aims: The aim of this work is to compare the performance of three reaction network integration methods used in stellar nucleosynthesis calculations. These are the Gear's backward differentiation method, Wagoner's method (a 2nd-order Runge-Kutta method ...
José, Jordi +2 more
core +1 more source