Results 131 to 140 of about 3,110,250 (305)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Multilayer Network Analysis of Nuclear Reactions. [PDF]

Sci Rep, 2016
Zhu L, Ma YG, Chen Q, Han DD.
europepmc   +1 more source

Theory of nuclear reactions /

, 1996
The authors decided to write this book when they could find no other texts for a course on non-relativistic nuclear reactions. It combines a thorough theoretical approach with applications to recent experimental results.
Fröbrich, Peter,, Lipperheide, Reinhard
core  

Dynamics of damped nuclear reactions [PDF]

, 1982
The nucleon-exchange model for damped nuclear reactions is briefly reviewed in the framework of macroscopic transport theory.
Randrup, J.
core  

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Generating keV ion distributions for nuclear reactions at near solid-density using intense short-pulse lasers. [PDF]

Nat Commun, 2019
Kemp AJ, Wilks SC, Hartouni EP, Grim G.
europepmc   +1 more source

Introduction to Nuclear Engineering and Ionizing Radiation

, 2019
This course provides an introduction to nuclear science and its engineering applications. It describes basic nuclear models, radioactivity, nuclear reactions and kinematics; covers the interaction of ionizing radiation with matter, with an emphasis on ...
Short, Michael
core  

Theory of hybrid nuclear reactions [PDF]

, 1983
A theory of hybrid nuclear reactions, which are partially direct and partially compound, is presented. We review first the formulation of the theory, based on the optical theorem, and then its applications to a few example reactions.
Udagawa, T.
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source