Results 1 to 10 of about 30,972 (212)

Novel NR2F1 variant identified by whole-exome sequencing in a patient with Bosch–Boonstra–Schaaf optic atrophy syndrome

Indian Journal of Ophthalmology, 2022
Bosch–Boonstra–Schaaf optic atrophy syndrome (BBSOAS) is an extremely rare autosomal dominant disorder characterized by intellectual disability, developmental delay, seizures, hypotonia, hearing loss, and optic nerve atrophy.
Ayca Kocaaga, Sevgi Yimenicioglu, Haluk Hüseyin Gürsoy   +2 more
doaj   +1 more source

METTL3 inhibits inflammation of retinal pigment epithelium cells by regulating NR2F1 in an m6A-dependent manner

Frontiers in Immunology, 2022
N6-metyladenosine (m6A) RNA methylation has been proven to be involved in diverse biological processes, but its potential roles in the development of lipopolysaccharide (LPS) induced retinal pigment epithelium (RPE) inflammation have not been revealed ...
Jiayu Meng, Jiayu Meng, Jiayu Meng, Xianyang Liu, Xianyang Liu, Xianyang Liu, Shiyun Tang, Shiyun Tang, Shiyun Tang, Yusen Liu, Yusen Liu, Yusen Liu, Chenyang Zhao, Chenyang Zhao, Chenyang Zhao, Qian Zhou, Qian Zhou, Qian Zhou, Na Li, Shengping Hou, Shengping Hou, Shengping Hou   +21 more
doaj   +1 more source

Transcriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice Isoforms

Drug Metabolism And Disposition, 2021
Carboxylesterase 1 (CES1) is the predominant carboxylesterase in the human liver, involved in metabolism of both xenobiotics and endogenous substrates.
J. M. Collins, Rong Lu, Xinwen Wang, Hao‐Jie Zhu, Danxin Wang   +4 more
semanticscholar   +1 more source

Nuclear receptor subfamily 1 group D member 1 suppresses the proliferation, migration of adventitial fibroblasts, and vascular intimal hyperplasia via mammalian target of rapamycin complex 1/β-catenin pathway

Clinical and experimental hypertension, 2023
Background In-stent restenosis hardly limits the therapeutic effect of the percutaneous vascular intervention. Although the restenosis is significantly ameliorated after the application of new drug-eluting stents, the incidence of restenosis remains at a
Ke Peng, Mingliang Wang, Jun Wang, Qiang Wang, De Li, Xiongshan Sun, Yongjian Yang, Dachun Yang   +7 more
semanticscholar   +1 more source

A coregulatory network of NR2F1 and microRNA-140. [PDF]

PLoS ONE, 2013
Both nuclear receptor subfamily 2 group F member 1 (NR2F1) and microRNAs (miRNAs) have been shown to play critical roles in the developing and functional inner ear.
David Y Chiang, David W Cuthbertson, Fernanda R Ruiz, Na Li, Fred A Pereira   +4 more
doaj   +1 more source

LncRNA nuclear receptor subfamily 2 group F member 1 antisense RNA 1 (NR2F1-AS1) aggravates nucleus pulposus cell apoptosis and extracellular matrix degradation

Bioengineered, 2022
Emerging reports uncover that long noncoding RNAs (lncRNAs) help regulate intervertebral disc degeneration (IVDD). Here, we probe the function of lncRNA nuclear receptor subfamily 2 group F member 1 antisense RNA 1 (NR2F1-AS1) in IVDD.
Longlong Du, Xuefeng Li, Q. Gao, Puwei Yuan, Yindi Sun, Yingpu Chen, Bo Huang, Yu Deng, Baohui Wang   +8 more
semanticscholar   +1 more source

DNA methylation of the glucocorticoid receptor gene predicts substance use in adolescence: longitudinal data from over 1000 young individuals

Translational Psychiatry, 2021
Early life stress has been linked to increased methylation of the Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1) gene, which codes for the glucocorticoid receptor.
Elena Raffetti, Philippe Anastasios Melas, Anton Jonatan Landgren, Filip Andersson, Yvonne Forsell, Catharina Lavebratt, Maria Rosaria Galanti   +6 more
doaj   +1 more source

Nuclear Receptor Subfamily 2 Group E Member 3 (NR2E3): Role in Retinal Development and Disease

Genes, 2023
NR2E3 is a nuclear hormone receptor gene required for the correct development of the retinal rod photoreceptors. Expression of NR2E3 protein in rod cell precursors suppresses cone-specific gene expression and, in concert with other transcription factors ...
Maria Toms, Natasha C. Ward, M. Moosajee
semanticscholar   +1 more source

Incomplete thermal ablation-induced up-regulation of transcription factor nuclear receptor subfamily 2, group F, member 6 (NR2F6) contributes to the rapid progression of residual liver tumor in hepatoblastoma

Bioengineered, 2021
Hepatoblastoma is a kind of extreme malignancy frequently diagnosed in children. Although surgical resection is considered as the first-line treatment for hepatoblastoma, a relatively large population of patients have lost the preferred opportunity for ...
Jin-Shu Pang, Dong-Yue Wen, R. He, Gang Chen, P. Lin, Jinhua Li, Yujia Zhao, Linyong Wu, Jun-Hong Chen, Yun He, Li-Ting Qin, Jia-Bo Chen, Yong Li, Hong Yang   +13 more
semanticscholar   +1 more source

High resolution melting analysis of the NR1I3 genetic variants: Is there an association with neonatal hyperbilirubinemia?

Gene, 2015
Constitutive androstane receptor (CAR) encoded by the nuclear receptor subfamily 1, group I, member 3 (NR1I3) gene regulates the elimination of bilirubin through activating the components of the bilirubin clearance pathway.
Tian Pei Cheung, H. Van Rostenberghe, Rosliza Ismail, Noor Namirah Nawawi, N. Abdullah, N. Ramli, N. R. Ibrahim, Noorizan Hj Abd Majid, Narazah Mohd Yusoff, H. Nishio, Surini Yusoff   +10 more
semanticscholar   +1 more source