Fruit respiration: putting alternative pathways into perspective
Summary Over the past century, research has significantly advanced our understanding of fruit respiration, from (eco)physiological processes to molecular mechanisms. This review focuses on the functional relevance and regulatory roles of mitochondrial alternative respiratory pathways (ARPs) during fruit growth and ripening.
Ariadna Iglesias‐Sanchez +4 more
wiley +1 more source
The orphan nuclear receptor NR4A3 is dispensable for resident memory CD8+ T-cell generation. [PDF]
Odagiu L +4 more
europepmc +1 more source
Imperatorin Mitigates Rosacea‐Like Inflammation by Modulating the Crosstalk Between JNK1 and STAT1
IMP treatment disrupts the interaction between JNK1 and STAT1, thereby attenuating STAT1 activity. This interference subsequently diminishes the phosphorylation and nuclear translocation of STAT1, which ultimately results in a reduced production of inflammatory cytokines and chemokines.
Xiaoxue Wang, Zexin Zhu
wiley +1 more source
Targeting IL6-Edn1-FoxO1 axis enables lung growth in mechanically ventilated newborn mice. [PDF]
Hirani D +23 more
europepmc +1 more source
NR4A3 (nuclear receptor subfamily 4, group A, member 3)
G. Stenman
semanticscholar +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Decoding HuH-7: a comprehensive genetic and molecular portrait of a widely used hepatocellular carcinoma model. [PDF]
Luis DD +9 more
europepmc +1 more source
NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source
Internalization-related host factors of common respiratory viruses. [PDF]
Lv Q, Xie Z, Xu L.
europepmc +1 more source
Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques
Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang +12 more
wiley +1 more source

