Results 161 to 170 of about 545,425 (311)

Risk communication between experts and the public: perceptions and intentions [PDF]

This paper develops a conceptual and theoretical analysis of risk communication in cases where experts and the public have widely divergent views of the dimensions of a risk.
Sjöberg, Lennart
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Mesenteric desmoid tumor with diagnostic challenge mimicking a malignant small intestinal tumor: a case report. [PDF]

Int J Surg Case Rep
Tokumaru T, Tabuchi M, Uemura S, Tamura S, Iwata J, Okabayashi T.   +5 more
europepmc   +1 more source

Nuclear Safeguards Education for European Nuclear Engineering Students

, 2006
The knowledge retention problem in the nuclear field was acknowledged by the Organization for Economic Co-operation and Development (OECD) in 2000. ESARDA, the European Safeguards Research and Development Association (http://www.jrc.cec.eu.int/esarda ...
JANSSENS-MAENHOUT Greet, BRIL Louis-Victor, GONCALVES Joao   +2 more
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

THE ENIGMA OF PAKISTAN'S NUCLEAR DETERRENCE: AN ALTERNATE PERSPECTIVE

Margalla Papers
Pakistan has developed its nuclear and missile programmes primarily in response to perceived threats from India. Pakistani officials claim that these capabilities are for self-defence, aiming to deter India from initiating a war.
Aezaz Aizad Amin
doaj  

SynClear: A one-step synchronous clearing and labeling strategy for multiscale 3D brain mapping. [PDF]

Mater Today Bio
Xiao X, Ma C, Wang Y, Zhu J, Chen J, Li S, Wang Y, Gong W, Si K.   +8 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source