Results 171 to 180 of about 959,641 (315)

Emerging Functions of the Repeat Genome in Nuclear Structure: A View from the Human Karyotype. [PDF]

Annu Rev Genomics Hum Genet
Hall LL, Smith KP, Lawrence JB.
europepmc   +1 more source

Replication timing and nuclear structure. [PDF]

Curr Opin Cell Biol, 2018
Fu H, Baris A, Aladjem MI.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Nuclear Structure, Size Regulation, and Role in Cell Migration. [PDF]

Cells
Li Y, Ge S, Liu J, Sun D, Xi Y, Chen P.
europepmc   +1 more source

Gene regulation through dynamic actin control of nuclear structure. [PDF]

Exp Biol Med (Maywood), 2019
Sankaran J, Uzer G, van Wijnen AJ, Rubin J.   +3 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Editorial: The Future of Nuclear Structure: Challenges and Opportunities in the Microscopic Description of Nuclei

Frontiers in Physics, 2021
Luigi Coraggio, Saori Pastore, Carlo Barbieri, Carlo Barbieri, Carlo Barbieri   +4 more
doaj   +1 more source

Divergent Contribution of Cytoplasmic Actins to Nuclear Structure of Lung Cancer Cells. [PDF]

Int J Mol Sci
Shagieva G, Dugina V, Burakov A, Levuschkina Y, Kudlay D, Boichuk S, Khromova N, Vasileva M, Kopnin P.   +8 more
europepmc   +1 more source

Spectrin and its interacting partners in nuclear structure and function. [PDF]

Exp Biol Med (Maywood), 2018
Lambert MW.
europepmc   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source