Results 201 to 210 of about 3,326,409 (352)
Pakistan's Nuclear Threshold: Not as Low as Perceived [PDF]
At slightest pretext, Pakistan threatens to use nuclear weapons against anyone it feels insecure, and more so against India.[1] The introduction of tactical nuclear weapons (TNWs) into its inventory has been portrayed to have sufficiently lowered its ...
Mishra, Sitakanta
core
Design of a course on the medical consequences of nuclear war
ChristineK. Cassel+2 more
openalex +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
Joseph Masco, The Nuclear Borderlands. The Manhattan Project in Post-Cold War New Mexico. Princeton, Princeton University Press, 2006, 438 p., bibliogr., index. [PDF]
Ariane Bélanger‐Vincent
openalex +1 more source
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo+2 more
wiley +1 more source
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source
Five Days In August - How World War II Became A Nuclear War
Stephen K. Stein
openalex +3 more sources
Highly efficient nuclear DNA typing of the World War II skeletal remains using three new autosomal short tandem repeat amplification kits with the extended European Standard Set of loci [PDF]
Irena Zupanič Pajnič+4 more
openalex +1 more source
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy+14 more
wiley +1 more source
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang+7 more
wiley +1 more source