Results 121 to 130 of about 929 (201)
Advanced Science, EarlyView.In brief. Yan et al. demonstrated that the excess lactate produced by the enhanced glycolysis pathway in esophageal cancer can lactylate H3K23, H3K23la can be enriched in the WNK1 promoter region to promote WNK1 expression, thereby increasing the phosphorylation of the p‐H3 Ser10 site, and p‐H3S10 can be enriched in the AKT1 promoter region to promote ...
Mingyang Yan +12 more
wiley +1 more source
Advanced Science, EarlyView.Sepsis‐triggered lactate accumulation induces pathological white adipose tissue browning. Lactate activates adipocyte GPR81 to sequentially upregulate CTRP6‐p38 signalling and UCP1 expression. This cascade exacerbates sepsis‐associated metabolic disorders.
Chunliang Zheng +4 more
wiley +1 more source
NUB1 Regulates Muscle Atrophy in Lung Cancer Cachexia via NF‐κB Signaling Pathway
Advanced Science, EarlyView.ABSTRACT Cancer‐associated cachexia (CAC) is a devastating multifactorial syndrome characterized by progressive skeletal muscle atrophy. Its mechanisms remain incompletely clarified, with limited effective therapeutic targets. NUB1, a negative regulator of ubiquitin‐like proteins mediating protein degradation, has not been fully elucidated in CAC ...
Yuqi Han +13 more
wiley +1 more source
Gradient‐Oxidized Bacterial Cellulose for Self‐Sustained Soil Moisture Sensing
Advanced Science, EarlyView.An asymmetric encapsulated bacterial cellulose device integrates a gradient‐oxidized BC framework with a LiCl‐doped Ecoflex hygroscopic layer, enabling self‐powered soil moisture monitoring through directional ion transport. The device sustains stable hydrovoltaic output, supports deep‐learning humidity classification, and fully biodegrades in soil ...
Nan Zhou +10 more
wiley +1 more source
Intelligent Polymer Electrolytes for Next‐Generation Zinc‐Based Energy Storage Devices
Advanced Science, EarlyView.Intelligent polymer electrolytes are organized into a three‐level hierarchy that advances zinc‐based energy storage from passive ion conduction toward active, adaptive, and intelligent operation. Molecular regulation of Zn+ coordination, water activity, desolvation, ion flux, and interfaces underpins adaptive self‐healing, anti‐freezing, adhesion, and ...
Sanath Kumar +4 more
wiley +1 more source
Advanced Electronic Materials, EarlyView.Composite‐based flexible electronics integrate biodegradable polymers, conductive networks, and multilayer device architectures to balance electrical performance, mechanical durability, and controlled degradation. Interfacial engineering and encapsulation regulate transport stability and operational lifetime, while programmed disassembly enables ...
Sayam, Sangho Cho
wiley +1 more source
Mechanochemical Defluorination of Polytetrafluoroethylene (PTFE) With Base Metals
Angewandte Chemie, EarlyView.Polytetrafluoroethylene (PTFE) mechanochemically reacts with safe‐to‐handle, abundant, and inexpensive base metals Zn and Al, as well as with metals like Cd and Pb, to produce sp2‐carbon and industrially important metal fluorides. The reactivity presents PTFE as a mechanochemical fluorination agent, with opportunities for closed‐loop reductive ...
Anže Zupanc +10 more
wiley +2 more sources
Advanced Energy Materials, EarlyView.Bio‐based gel polymer electrolytes promise sustainable, mechanically adaptable zinc–air batteries, yet their progress is constrained by inconsistent characterization. This review critically links formulation, structure, interfaces, and cell performance, identifies methodological gaps under alkaline operating conditions, and proposes application ...
Matteo Milanesi +6 more
wiley +1 more source
Coacervate Droplet Sequestration of Heterogeneous Nanoplastics With Elastin‐Like Polypeptides
Angewandte Chemie, EarlyView.Phase‐separated polypeptide droplets captured incidental nanoplastics as a reusable nanoplastic sink. The engineered droplets selectively partitioned nanoplastics and exhibited unique interactions depending on droplet type and nanoplastic identity, establishing biopolymer coacervates as a potential platform for nanoplastic characterization and removal.
Natalie R. Ling +2 more
wiley +2 more sources