Results 201 to 210 of about 121,610 (336)

Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler   +4 more
wiley   +2 more sources

Metal‐Coordination Specificity and Structural Dynamics of C. elegans Metallothionein I: Insights From 3D Modeling and MD Simulations

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 2, Page 620-632, February 2026.
ABSTRACT Metallothioneins (MTLs) are small, cysteine‐rich proteins known for their ability to bind metal ions and exhibit flexible, disordered structures. The structural and functional characteristics of metallothionein I (MTL‐1) from Caenorhabditis elegans were investigated, focusing on its behavior in both metal free (MTL‐1 Apo) and metal‐bond states
Nilvea Ramalho de Oliveira   +4 more
wiley   +1 more source

‘Sweet poison’ and ‘mild medicine’: Different effects of collective narcissism and collective self‐esteem on ingroup versus outgroup conspiracy beliefs

open access: yesBritish Journal of Psychology, Volume 117, Issue 1, Page 356-377, February 2026.
Abstract Collective narcissism and non‐narcissistic ingroup positivity (notably collective self‐esteem) are associated differently with conspiracy beliefs. We conducted three cross‐sectional surveys in China and the United States that distinguished between ingroup and outgroup conspiracy beliefs, to explore the intricate relationships and underlying ...
Jia‐Yan Mao   +3 more
wiley   +1 more source

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