Results 51 to 60 of about 271,090 (364)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Ice nucleation under cirrus cloud conditions [PDF]

open access: yes, 2012
Cirrus are thin upper tropospheric clouds that are composed entirely of ice particles. Due to their extensive coverage of the Earth’s surface, they have a significant impact on the Earth’s radiative balance.
Wilson, Theodore W
core  

Laboratory study on new particle formation from the reaction OH + SO₂: influence of experimental conditions, H₂O vapour, NH₃ and the amine tert-butylamine on the overall process [PDF]

open access: yes, 2010
Nucleation experiments starting from the reaction of OH radicals with SO2 have been performed in the IfT-LFT flow tube under atmospheric conditions at 293±0.5 K for a relative humidity of 13–61%.
Gruener, A.   +37 more
core   +1 more source

Nucleation-dependent aggregation kinetics of yeast Sup35 fragment GNNQQNY [PDF]

open access: yes, 2021
An N-terminal hepta-peptide sequence of yeast prion protein Sup35 with the sequence GNNQQNY is widely used as a model system for amyloid fibril formation.
Ashwani K Thakur (16287974)   +3 more
core   +2 more sources

Earthquake Nucleation Processes Across Different Scales and Settings [PDF]

open access: yes, 2020
Extended nucleation phases of earthquakes have been regularly observed, yet the underlying mechanisms governing the initiation phase of rupture are yet to be understood in detail.
Bentz, Stephan
core   +1 more source

Study of the Kinetics of Reduction of IrO2 on TiO2 (Anatase) by Temperature-Programmed Reduction

open access: yesInorganics, 2023
The interaction between IrO2 and TiO2 (anatase) in non-isothermal reduction conditions has been studied by the temperature programmed reduction technique.
Shahad Batubara   +3 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Concepts of Nucleation in Polymer Crystallization

open access: yesCrystals, 2021
Nucleation plays a vital role in polymer crystallization, in which chain connectivity and thus the multiple length and time scales make crystal nucleation of polymer chains an interesting but complex subject. Though the topic has been intensively studied
Jun Xu, Günter Reiter, Rufina G. Alamo
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Characterization of aerosol particles by their heterogeneous nucleation [PDF]

open access: yes, 2022
S.732-735An expansion type cloud condensation nucleus counter / Kevin spectrometer has been operated with and various organic liquids.
Windt, H., Holländer, W., Dunkhorst, W.
core  

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