Results 131 to 140 of about 119,828 (299)

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Sialic acid utilization by Cronobacter sakazakii

, 2013
Background: The Cronobacter genus is composed of seven species, and can cause infections in all age groups. Of particular concern is C. sakazakii, as this species is strongly associated with severe and often fatal cases of necrotizing enterocolitis and ...
Forsythe, S, Hariri, S, Stephen Forsythe, Joseph, S, Susan Joseph, Sumyya Hariri, Masood, N, Naqash Masood   +7 more
core   +1 more source

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

Advanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng, Jiahao Lin, Qiushuang Zhang, Xiangdong Zhang, Yicong Dai, Jinghong Li   +5 more
wiley   +1 more source

Peptide‐Peptide Nucleic Acid Hybrid Hydrogel Based on Sequence Programmable Morphological Change for DNA Data Storage

Small Structures
Peptide‐based hydrogels provide biocompatible, stimuli‐responsive platforms, while peptide‐DNA hybrids extend programmability through hybridization‐driven crosslinking. However, nucleobase incorporation can influence peptide self‐assembly pathways.
Huiling Lei, Jinsheng Li, Zixiao Zhang, Zi’an Lin, Guangxu Zhang, Jianjian Huang, Shuhan Dai, Guojiao Wu, Hongmei Liu, Yuzhou Wu   +9 more
doaj   +1 more source

DNA Nanoarray for Multiplexed RNA Detection With Single‐Molecule Readout

Advanced Science, EarlyView.
A carrier‐based DNA nanoarray integrates programmable nucleic acid hybridization with solid‐state nanopore readout for direct RNA detection at single‐molecule resolution. A ternary encoding system enables 27 carriers with 81 addressable sensing sites, allowing the simultaneous identification of targets spanning a wide size range, from short microRNAs ...
Yunxuan Li, Yesheng Wang, Chunmiao Yu, Siyu Hou, Elli Mylona, Plamena Naydenova, Jingyuan Zhao, Hong Yuan, Jingsong Duan, Hendrik F. P. Runge, Stephen Baker, Jinbo Zhu, Ulrich F. Keyser   +12 more
wiley   +1 more source

Label-Free Detection of Zeptomol miRNA via Peptide Nucleic Acid Hybridization Using Novel Cyclic Voltammetry Method. [PDF]

Sensors (Basel), 2020
Takase S, Miyagawa K, Ikeda H.
europepmc   +1 more source

Metaphase and Interphase Cytogenetics with Alu-PCR-amplified Yeast Artificial Chromosome Clones Containing the BCR Gene and the Protooncogenes c-raf-1, c-fms, and c-erbB-21 [PDF]

, 1992
A human yeast artificial chromosome (YAC) library was screened by polymerase chain reaction with oligonucleotide primers defined for DNA sequences of the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erB-2.
Olson, Maynard V., Riethman, Harold C., Green, Eric D., Becher, Reinhard, Taniwaki, Masafumi, Michael R. Speicher, Speicher, Michael R., Cremer, Thomas, Christoph Lengauer, Eric D. Green, Konecki, David, Maynard V. Olson, David Konecki, Reinhard Becher, Harold C. Riethman, Lengauer, Christoph, Masafumi Taniwaki, Thomas Cremer   +17 more
core  

Emergent Properties and Functions of Nanoconfined Nucleic Acid Architectures

, 2015
The facile ability of DNA to self-assemble has enabled the creation of complex architectures with diverse functions on surfaces or in solution. This approach provides a powerful design tool for the development of nanoscale devices with transformative ...
Lucia Coral, Redhu, Shiv K., Nicholson, Allen W., CASTRONOVO, MATTEO, Allen W. Nicholson, Vincenzo Carnevale, STOPAR, ALEX, Matteo Castronovo, CORAL, LUCIA, Carnevale, Vincenzo, Shiv K. Redhu, Alex Stopar   +11 more
core   +1 more source

Allosteric DNAzyme‐Enabled Sensitive and Multiplex Detection of Biomarkers for Rapid Diagnosis of Urinary Tract Infections

Advanced Science, EarlyView.
A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen, Chenzhi Shi, Xiaowei Ma, Pengfei Hou, Haomin Zhang, Juanxiu Qin, Li Pan, Guilin Li, Lifei Gao, Qian Ma, Donglei Yang, Min Li, Pengfei Wang   +12 more
wiley   +1 more source

Nucleic Acid Hybridization Enhanced Luminescence for Rapid and Sensitive RNA and DNA Based Diagnostics

Long-lived emissive nucleic acid probes are widely used in biochemical analysis due to their programmable structures, high signal-to-background ratio, and high sensitivity.
Niko Hildebrandt (1399045), Zongwen Jin (1920373), Cui Liu (154987), Mingzhen Zhang (1735672), Xue-Feng Yu (1639420), Xiaoyuan Wei (7105331), Huimin Zhang (1428787), Qing-Ying Luo (7500431)   +7 more
core   +1 more source