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Nucleic acid and protein sequence databases

Bioinformatics, 1985
Nucleic acid and protein sequences contain a wealth of information of interest to molecular biologists. The advent of molecular sequence databases provides a unique opportunity for the computer analysis of all available sequences. Sequence databases serve two main functions: (i) to facilitate comparisons with newly determined sequences, and (ii) to act
M.J. Bishop, G.G. Kneale
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Introduction to Nucleic Acid Sequencing

2019
Determining the order of nucleotide in the biological macromolecules has laid the foundation for understanding the biology of an organism. Over the last 50 years, genomics has been revolutionized with the researchers producing newer techniques and technologies leading to innovations in the field of DNA sequencing.
Francis Amirtharaj   +2 more
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Nucleic Acid Sequence Bank

Science, 1980
In the report by T. Kakunaga and J. D. Crow (25 July, p. 505), Fig. 1 on page 506 should have been printed as follows: [See figure in the PDF file]
Bruce C. Orcutt   +5 more
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Doublet frequencies in sequenced nucleic acids

Journal of Molecular Evolution, 1975
A doublet frequency count (set of frequencies of the 16 possible two-base sequences) can be calculated from the experimentally determined overall sequence of a nucleic acid. In this paper, a statistical methodology is developed for comparing such counts with random, with others of the same type or with doublet proportions found in whole DNAs.
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Nucleic acid sequence databases

Bioinformatics for Everyone, 2022
M. Sofi, Afshan Shafi, K. Z. Masoodi
semanticscholar   +1 more source

Nucleic Acid Sequence Determination

1980
It is often emphasised how closely the structure and function of biological materials are related to each other. This is certainly true for all biological macromolecules, but to some extent it is also true for any chemical substance: whether it takes part in a simple chemical reaction or in a complex biological process, the function of the molecule is ...
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Sequences in Genetic Nucleic Acids

1973
The basic chemical material of the gene is DNA and all the information for the developing organism is contained in the form of a specific nucleotide sequence in this DNA. In order to understand the gene more fully and the way in which the information is encoded it is necessary to study these nucleotide sequences.
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Nucleic acid sequence analysis software for microcomputers

Analytical Biochemistry, 1990
It is clear that a computer-aided data control system is required for even small laboratories generating nucleic acid data. While the molecular biologist at many universities and large research institutions has access to mainframe computers and nucleic acid sequence analysis software, many find it more convenient to perform sequence analysis on ...
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A novel method for nucleic acid sequence determination

Journal of Theoretical Biology, 1988
We describe a novel sequencing methodology which should be readily and completely automated. The method relies on fragmentation of a nucleotide or deoxynucleotide sequence into short fragments, and subsequent quantitation of the fragments by hybridization to oligo-deoxynucleotides on a solid support.
Geoff C. Smith, William Bains
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Nucleic Acids (DNA) Sequencing, Transcriptional

2006
Transcriptional Sequencing (TS) is a novel DNA sequencing method based on the chain termination method using RNA Polymerase (RNAP). Transcriptional sequencing differs considerably from conventional cycle sequencing methods using DNA Polymerases (DNAPs) with 2′-deoxyribonucleotide triphosphates (2′-dNTPs) and 2′, 3′-dideoxyribonucleotide triphosphates ...
Kazuhiro Shibata   +2 more
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