Results 121 to 130 of about 263,091 (259)

Comparative Diagnostic Yield of Rapid Immunoassay-Based Tests and Nucleic Acid Testing for Transfusion-Transmissible Infections in a Tertiary Care Setting. [PDF]

Cureus
Singh DK, Singh R, Singh A, Tiwari V, Shukla S, Kumar G, Kumar M.   +6 more
europepmc   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Prevalence of Transfusion-Transmitted Viral Infections Among Blood Donors in Riyadh, Saudi Arabia: A Comparative Analysis of Nucleic Acid Testing and Serological Screening. [PDF]

J Clin Med
Aldhalaan RM, Sajid MR, Raddaoui L, Saleem RA, Odeh N, Elshaer R, Aldosari S, Ikram MF.   +7 more
europepmc   +1 more source

The impact of community nucleic acid testing on infection in residential compounds during a city-wide lockdown. [PDF]

Sci Rep, 2023
Jia Z, Hu J, Lian T, Qian L, Yu W, Zhang C.   +5 more
europepmc   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Vertical-flow tearable paper-tape rolls for scalable multiplexed point-of-care nucleic acid testing. [PDF]

Microsyst Nanoeng
Shi S, Wang Z, Yao Y, Gao Y, Tang J, Zhang C, Bai H, Du Z, Hu J, Su Y, Chen G, Cai X, Ying B, Chang L, Hu W, Wang Y.   +15 more
europepmc   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Comparison of nucleic acid testing and enzyme-linked immunosorbent assay in screening Hepatitis-B Virus in blood samples. [PDF]

Pak J Med Sci
Xin H, Luo W, Zhao P.
europepmc   +1 more source

How to better select SARS-CoV-2 preservation solution of virus nucleic acid testing. [PDF]

J Clin Lab Anal, 2023
Duan X, Huang L, Wang X, Ping Y, Yu P, Liu W, Xie Y, Tao Z.   +7 more
europepmc   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source