Results 201 to 210 of about 263,091 (259)

Nucleic Acid Tests for Clinical Translation

Chemical Reviews, 2021
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are natural biopolymers composed of nucleotides that store, transmit, and express genetic information. Overexpressed or underexpressed as well as mutated nucleic acids have been implicated in many diseases.
Fan Li, Qiang Xia, Xiaolei Zuo
exaly   +3 more sources

Nucleic Acids and Protamine in Salmon Testes

1968
Publisher Summary This chapter focuses on the presence of nucleic acids and protamine in Salmon testes. It highlights the approach of the centenaries of the discoveries of deoxyribonucleic acid (nuclein) and of protamine. The subsequent relative lack of research on the biochemistry of the salmon testes is in all probability because of the limited ...
G H, Dixon, M, Smith
openaire   +2 more sources

Nucleic acid testing

Nature, 1997
DNA research techniques continue to proliferate and examples announced this week include tools for sequence analysis, DNA and RNA probes and cDNA panels for gene cloning.
openaire   +1 more source

Nucleic acid testing: Update and applications

Seminars in Hematology, 2001
Nucleic acid testing (NAT) holds the promise of closing the window of infectiousness for hepatitis C virus (HCV) and the human immunodeficiency virus (HIV) in the general blood supply. Pioneering work by the source plasma industry with NAT for hepatitis A virus (HAV), hepatitis B virus (HBV), and parvovirus B19 suggests that, in the future, the risk of
openaire   +2 more sources

Yield and future issues of nucleic acid testing

Transfusion Clinique et Biologique, 2001
Despite the much lower actual yield than that estimated for hepatitis C virus (HCV) and human immunodeficiency virus (HIV) nucleic acid testing (NAT)-only positives in the USA and Germany, look-back procedures have revealed that no HCV transmission has occurred in Germany since the introduction of NAT.
W K, Roth, E, Seifried
openaire   +2 more sources

Nucleic acid testing for emerging viral infections

Transfusion Medicine, 2002
Summary. The development of new technologies leads to the discovery of new viruses. For each of these new infectious agents, relevance to transfusion, including transmissibility by transfusion, pathogenicity, prevalence in blood donors, persistence and the availability of screening assays needs to be assessed.
J-P, Allain, I, Thomas, S, Sauleda
openaire   +2 more sources

Nucleic acid testing for transfusion-transmissible agents

Current Opinion in Hematology, 2000
Pooled nucleic acid testing for HIV and hepatitis C virus (HCV) has been successfully implemented in the United States. Reactive rates for nucleic acid testing (NAT) are comparable to those for serological testing. The combined yield for HIV and HCV RNA confirmed-positive, seronegative donations for the 1st year of testing has been 62 HCV NAT-reactive ...
openaire   +2 more sources

AI-empowered visualization of nucleic acid testing

Life Sciences
The visualization of nucleic acid testing (NAT) results plays a critical role in diagnosing and monitoring infectious and genetic diseases. The review aims to review the current status of AI-based NAT result visualization. It systematically introduces commonly used AI-based methods and techniques for NAT, emphasizing the importance of result ...
Zehua, Lu, Xiaogang, Wang, Junge, Chen
openaire   +2 more sources

Use of nucleic acid probes in genetic tests

Clinical Biochemistry, 1990
Advances in molecular genetics have led to the development of clinical assays for several genetic diseases. Two general testing approaches are available: direct detection of the genetic mutation or indirect detection using DNA markers close to, or within, the defective gene.
openaire   +2 more sources