Results 31 to 40 of about 263,091 (259)
Nucleic Acid Testing for the Detection of HBV DNA [PDF]
Hepatitis Monthly, 2011 Dear Editor, We read with interest the article by Arababadi et al. [1], which highlights different and important areas of concern in the management of occult hepatitis B (OBI). There are two relevant issues worthy of discussion. First, the authors described the variable prevalence of OBI in different geographical regions worldwide.
Yuen, MF, Lai, CL, Seto, WK
openaire +4 more sources
Frontiers in Cellular and Infection Microbiology, 2022 After the outbreak of SARS-CoV-2, nucleic acid testing quickly entered people’s lives. In addition to the polymerase chain reaction (PCR) which was commonly used in nucleic acid testing, isothermal amplification methods were also important nucleic acid ...
Meiying Tan +5 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Cyclophosphamide Tolerance as a Test for Antigenicity of Nucleic Acids [PDF]
Nature, 1970 IT has been generally thought that nucleic acids are unable to elicit an immune response without carrier protein and adjuvant1. We have recently succeeded in accelerating the spontaneous formation of antibodies to RNA and DNA in New Zealand mice with polyinosinic · polycytidylic acid (poly I·C) without carrier protein or additional adjuvant2.
Steinberg, A D +3 more
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Lab-on-a-Chip Devices for Nucleic Acid Analysis in Food Safety
MicromachinesLab-on-a-chip (LOC) devices have been developed for nucleic acid analysis by integrating complex laboratory functions onto a miniaturized chip, enabling rapid, cost-effective, and highly sensitive on-site testing.
Inae Lee, Hae-Yeong Kim
doaj +1 more source
Improving Detection Efficiency of SARS-CoV-2 Nucleic Acid Testing
Frontiers in Cellular and Infection Microbiology, 2020 BackgroundSARS-CoV-2 nucleic acid testing (NAT) has been routinely used for COVID-19 diagnosis during this pandemic; however, there have been concerns about its high false negative rate.
Jie Zhang +10 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Scientific Reports, 2017 Management of curable sexually-transmitted infections (STI) such as Chlamydia can be revolutionized by highly sensitive nucleic acid testing that is deployable at the point-of-care (POC).
D. J. Shin +8 more
doaj +1 more source
A portable system for economical nucleic acid amplification testing
Frontiers in Bioengineering and Biotechnology, 2023 Introduction: Regular and rapid large-scale screening for pathogens is crucial for controlling pandemics like Coronavirus Disease 2019 (COVID-19). In this study, we present the development of a digital point-of-care testing (POCT) system utilizing ...
Hui Dong +10 more
doaj +1 more source