Results 201 to 210 of about 79,150 (267)
Biological Polymers: Evolution, Function, and Significance. [PDF]
Matange K+3 more
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Long-range electrostatic forces govern how proteins fold on the ribosome
Streit JO+6 more
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Thermodynamics of nucleic acids and their interactions with ligands
1. Introduction 2551.1 General thermodynamics 2562. Nucleic acid thermodynamics 2602.1 DNA duplexes 2612.2 RNA duplexes 2632.3 Hybrid DNA–RNA duplexes 2642.4 Hydration 2672.5 Conformational flexibility 2692.6 Thermodynamics 2723. Nucleic acid–ligand interactions 2773.1 Minor groove binders 2783.2 DNA intercalators 2843.3 Triple-helical systems 2883.3.1
Andrew N. Lane, Terence C. Jenkins
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[24] Thermodynamics of ligand-nucleic acid interactions
Ligand-and protein-DNA equilibria are extremely sensitive to solution conditions (e.g., salt, temperature, and pH), and, in general, the effects of different solution variables are interdependent (i.e., linked). As a result, an assessment of the basis for the stability and specificity of ligand-or protein-DNA interactions requires quantitative studies ...
Timothy M. Lohman, David P. Mascotti
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Statistical thermodynamics of nucleic acid melting transitions with coupled binding equilibria
AbstractEquations are developed to describe the shift in the temperature of the helix–coil transition when small molecules bind to nucleic acids. Included are high polymers, oligonucleotides, and oligomer–polymer interactions. The equations prescribe simple ways of plotting experimental data to evaluate transition and binding parameters.
Donald M. Crothers
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AbstractFor Abstract see ChemInform Abstract in Full Text.
Vladimir A. Basiuk
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Hydrodynamics, Thermodynamics and Scattering Properties: Nucleic Acids, Nucleosomes and Chromatin
Though the progress of both experimental and theoretical chemistry has been steady since the eighteenth century, it was only in our lifetime that the nature of the macromolecular state was clearly established. Until about fifty years ago it was generally believed that large, covalently bonded, well defined macromolecules do not exist, and only ill ...
Henryk Eisenberg
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Thermodynamics and Kinetics‐Directed Regulation of Nucleic Acid‐Based Molecular Recognition
AbstractNucleic acid‐based molecular recognition plays crucial roles in various fields like biosensing and disease diagnostics. To achieve optimal detection and analysis, it is essential to regulate the response performance of nucleic acid probes or switches to match specific application requirements by regulating thermodynamics and kinetics properties.
Yihao Liu+5 more
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