Results 201 to 210 of about 221,973 (265)
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A Mathematical Model of Nucleic Acid Thermodynamics
, 2018The DNA denaturation, the double-stranded DNA unwinding process, is a vital process for cells. The percentage of the denaturation is used as an index of organism complexity and it is the base of the DNA hybridisation technique, which provides a great deal of information.
Sonia Guarguagli, F. Pastrone
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Journal of the American Chemical SocietyFolding thermodynamics, quantitatively described using parameters such as ΔGfold°, ΔHfold°, and ΔSfold°, is essential for characterizing the stability and functionality of noncanonical nucleic acid structures but remains difficult to measure at the ...
Yuqin Wu +3 more
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Statistical thermodynamics of nucleic acid melting transitions with coupled binding equilibria
Biopolymers, 1971AbstractEquations are developed to describe the shift in the temperature of the helix–coil transition when small molecules bind to nucleic acids. Included are high polymers, oligonucleotides, and oligomer–polymer interactions. The equations prescribe simple ways of plotting experimental data to evaluate transition and binding parameters.
D. Crothers
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Kinetic and thermodynamic origins of osmolyte-influenced nucleic acid folding.
The Journal of Physical Chemistry B, 2015The influential role of monovalent and divalent metal cations in facilitating conformational transitions in both RNA and DNA has been a target of intense biophysical research efforts. However, organic neutrally charged cosolutes can also significantly alter nucleic acid conformational transitions.
Erik D. Holmstrom, N. Dupuis, D. Nesbitt
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Thermodynamics of Nucleic Acids Enclosed in Reverse Phase Vesicles
, 1984 Reverse micelles and vesicles mimic properties of biological membranes in the sense that they include a small water volume in a charged or in an at least polar surface formed by the hydrophilic headgroups of amphiphilic compounds. Membranes with this type of a surface form the cellular compartments which are the reaction vessels for most chemical ...
Bernhard Brosius +3 more
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Thermodynamic database supports deciphering protein–nucleic acid interactions
Trends in Biotechnology, 2023The thermodynamics of protein-nucleic acid interactions (PNIs) is crucial for elucidating the mechanisms of molecular recognition and pathological consequences. The Protein-Nucleic Acid Thermodynamics Database (PNATDB) is a database containing experimentally determined thermodynamic parameters along with sequence, structural, and function data, which ...
Long-Can Mei, Ge-Fei Hao, Guang-Fu Yang
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Journal of Physical Chemistry B, 2021
Biomolecular folding in cells can be strongly influenced by spatial overlap/excluded volume interactions (i.e., "crowding") with intracellular solutes.
Hsuan-Lei Sung, D. Nesbitt
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Biomolecular folding in cells can be strongly influenced by spatial overlap/excluded volume interactions (i.e., "crowding") with intracellular solutes.
Hsuan-Lei Sung, D. Nesbitt
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Protein-nucleic acid thermodynamic databases for specific uses.
Trends in biotechnology, 2023In response to Gromiha and Harini, we review the currently available thermodynamic databases for protein-nucleic acid interactions. These databases are designed for particular uses. We give general comments on them to facilitate browsing and exploration.
Long-Can, Mei +2 more
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Thermodynamics and kinetics of co-operative protein-nucleic acid binding
Journal of Molecular Biology, 1983 Fumiyuki Watanabe, Gerhard Schwarz
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