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Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases
Pharmacology & Therapeutics, 2000Nucleoside monophosphate kinases catalyze the reversible phosphotransferase reaction between nucleoside triphosphates and monophosphates, i.e., monophosphates are converted to their corresponding diphosphate form. These enzymes play an important role in the synthesis of nucleotides that are required for a variety of cellular metabolic processes, as ...
Anna Karlsson +2 more
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A short de novo synthesis of nucleoside analogs
Science, 2020Short path to a complex ring Nucleotide analogs are valuable tools and therapeutics because of their ability to interfere with processes such as DNA synthesis, which are vital to rapidly dividing cells and replicating viruses.
Michael Meanwell +7 more
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Journal of Chromatography A, 1980
Abstract The chromatographic parameters affectingthe reversed-phase high-performance liquid chromatographic (HPLC) separation of major and modified nucleosides with a μBondapak C 18 column have been studied. This investigation has resulted in the HPLC separation of eighteen nucleosides in a single analysis. The parameters studied include: the mobile
Kenneth C. Kuo +2 more
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Abstract The chromatographic parameters affectingthe reversed-phase high-performance liquid chromatographic (HPLC) separation of major and modified nucleosides with a μBondapak C 18 column have been studied. This investigation has resulted in the HPLC separation of eighteen nucleosides in a single analysis. The parameters studied include: the mobile
Kenneth C. Kuo +2 more
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Experientia, 1970
Mit N-Bromsuccinimid konnen Nukleoside in Dimethylformamid mit guter Ausbeute zu den in 5-Stellung bromierten Derivaten umgewandelt werden.
K. L. Nagpal, P. C. Srivastava
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Mit N-Bromsuccinimid konnen Nukleoside in Dimethylformamid mit guter Ausbeute zu den in 5-Stellung bromierten Derivaten umgewandelt werden.
K. L. Nagpal, P. C. Srivastava
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Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1974
Abstract The dipole moments of a series of model pyrimidine nucleosides were determined experimentally. Comparison was made between the experimental values and those vectorially calculated as a function of nucleoside conformation. This analysis alone does not permit the unequivocal determination of the conformation of the nucleoside in solution, but ...
Andrzej Rabczenko, I. Kulakowska
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Abstract The dipole moments of a series of model pyrimidine nucleosides were determined experimentally. Comparison was made between the experimental values and those vectorially calculated as a function of nucleoside conformation. This analysis alone does not permit the unequivocal determination of the conformation of the nucleoside in solution, but ...
Andrzej Rabczenko, I. Kulakowska
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ChemInform, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Vicente Gotor, Miguel Ferrero
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AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Vicente Gotor, Miguel Ferrero
openaire +4 more sources