Results 211 to 220 of about 262,017 (266)

An ancient Erysipelothrix rhusiopathiae genome recovered from 1400-year-old human remains in the Northern Caucasus. [PDF]

Sci Rep
Kritsky AA, Berezina NY, Ivanova AO, Sutormin DA, Botsmanov EI, Perevozchikova AA, Kadieva AA, Tsedilina TR, Kolesnik MV, Pavlova AV, Demidenko SV, Klimuk EI, Buzhilova AP, Severinov KV.   +13 more
europepmc   +1 more source

Shared genetic architecture of obesity and gastroesophageal reflux disease. [PDF]

Medicine (Baltimore)
Xiao L, Zhu D, Liu W.
europepmc   +1 more source

ViTrace detects viral signatures in tumor transcriptomes using a hybrid language model. [PDF]

Commun Biol
Zhou F, He Y, Yang F, Gu J, Sun F, Zhu S, Huang X, Wang Y.   +7 more
europepmc   +1 more source

Using pangenome variation graphs to improve mutation detection in a large DNA virus

Wright C, Tennakoon C, Lasecka-Dykes L, Downing T.   +3 more
europepmc   +1 more source

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Mapping single-nucleotide m6A by m6A-REF-seq

Methods, 2022
The past few years have witnessed rapid progress in the field of RNA modifications. As the most prevailing modification on eukaryotic mRNA, m6A is characterized to play a vital role in various cellular activities. However, limitations of the detection method impede functional studies of m6A. Here we introduce m6A-REF-seq, a powerful and straightforward
Hong-Xuan, Chen, Zhang, Zhang, Dong-Zhao, Ma, Li-Qian, Chen, Guan-Zheng, Luo   +4 more
openaire   +2 more sources

Cyclic Nucleotide Mapping of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels

ACS Chemical Biology, 2014
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels play a central role in the regulation of cardiac and neuronal firing rate, and these channels can be dually activated by membrane hyperpolarization and by binding of cyclic nucleotides. cAMP has been shown to directly bind HCN channels and modulate their activity.
Moller, Stefan, Alfieri, Andrea, Bertinetti, Daniela, Aquila, Marco, Schwede, Frank, Lolicato, Marco, Rehmann, Holger, Moroni, Anna, Herberg, Friedrich W.   +8 more
openaire   +5 more sources

Mapping oxidative DNA damage at nucleotide level

Free Radical Research, 1998
DNA damage induced by reactive oxygen species (ROS) is considered an important intermediate in the pathogenesis of human conditions such as cancer and aging. By developing an oxidative-induced DNA damage mapping version of the Ligation-mediated polymerase chain reaction (LMPCR) technique, we investigated the il vivo and in vitro frequencies of DNA base
H, Rodriguez, S A, Akman
openaire   +2 more sources