Results 281 to 290 of about 482,535 (309)
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Notochord to Nucleus Pulposus Transition
Current Osteoporosis Reports, 2015A tissue that commonly deteriorates in older vertebrates is the intervertebral disc, which is located between the vertebrae. Age-related changes in the intervertebral discs are thought to cause most cases of back pain. Back pain affects more than half of people over the age of 65, and the treatment of back pain costs 50-100 billion dollars per year in ...
Brian D. Harfe, Lisa Y. Lawson
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Journal of Biomaterials Applications, 2020
Extracellular matrix loss is one of the early manifestations of intervertebral disc degeneration. Stem cell-based tissue engineering creates an appropriate microenvironment for long term cell survival, promising for NP regeneration. We created a decellularized nucleus pulposus hydrogel (DNPH) from fresh bovine nucleus pulposus.
Lei Yu +6 more
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Extracellular matrix loss is one of the early manifestations of intervertebral disc degeneration. Stem cell-based tissue engineering creates an appropriate microenvironment for long term cell survival, promising for NP regeneration. We created a decellularized nucleus pulposus hydrogel (DNPH) from fresh bovine nucleus pulposus.
Lei Yu +6 more
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lncRNA HOTAIR upregulates autophagy to promote apoptosis and senescence of nucleus pulposus cells
Journal of Cellular Physiology, 2020Intervertebral disc degeneration (IDD) is a complex and chronic disease that involves disc cell senescence, death, and extracellular matrix (ECM) degradation.
Shengfeng Zhan +10 more
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Reflections on the Nucleus Pulposus
Rivista di Neuroradiologia, 1998The intervertebral disc is usually divided into two parts, the anulus fibrosus and the nucleus pulposus. However, they are not considered two separate anatomic parts since one is essentially part of the other and this should be borne in mind to understand the process of ageing.
Luigi Simonetti, C. Barbara
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Inflammatogenic Properties of Nucleus Pulposus
Spine, 1995The inflammatogenic properties of nucleus pulposus were assessed in two experimental models previously used for screening of inflammatogenic properties of other substances. This study was performed to assess the inflammatogenic properties of nucleus pulposus in models previously screened for other substances.Previous experimental studies, as well as ...
Strömberg J +5 more
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Spine, 2011
Both sequestrated nucleus pulposus (SNP) and the remaining nucleus pulposus (RNP) were studied from the discs of the same patient to evaluate apoptosis using immunohistochemical staining.To compare apoptosis of the SNP and the RNP in the disc of the same patient.Many studies have been conducted on the natural history and apoptosis of the herniated ...
Bae-Gyun Kim +4 more
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Both sequestrated nucleus pulposus (SNP) and the remaining nucleus pulposus (RNP) were studied from the discs of the same patient to evaluate apoptosis using immunohistochemical staining.To compare apoptosis of the SNP and the RNP in the disc of the same patient.Many studies have been conducted on the natural history and apoptosis of the herniated ...
Bae-Gyun Kim +4 more
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Spine, 1996
A new technique to measure the viscoelastic behavior of the nucleus pulposus in shear was used to assess its solid and fluid characteristics.To review existing knowledge on mechanical behaviors of the nucleus pulposus, and to develop a new technique to study the viscoelastic behaviors of isolated nucleus pulposus samples in torsional (pure) shear under
Van C. Mow +3 more
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A new technique to measure the viscoelastic behavior of the nucleus pulposus in shear was used to assess its solid and fluid characteristics.To review existing knowledge on mechanical behaviors of the nucleus pulposus, and to develop a new technique to study the viscoelastic behaviors of isolated nucleus pulposus samples in torsional (pure) shear under
Van C. Mow +3 more
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Hernia of the Nucleus Pulposus
The British Journal of Radiology, 1934In the radiological examination of the spine one frequently sees in association with kyphoses very varied contours of the upper and lower vertebral margins. They may appear wavy or show irregular sclerotic patches or even appear notched. These irregularities are apt to be dismissed, the mild ones as variations of the normal and the more gross ones ...
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Antibiotic Penetration into Rabbit Nucleus Pulposus
Spine, 1987A rabbit model was used to determine the penetration of four commonly used antibiotics (clindamycin, tobramycin, cephalothin, and oxacillin) into the nucleus pulposus after receiving an 8-hour course of intramuscular antibiotic injections. Clindamycin and tobramycin achieved therapeutic levels in the nucleus pulposus and both were present in greater ...
Richard H. Rothman +3 more
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Spine, 2003
Intact rabbit lumbar intervertebral discs were examined histologically.To demonstrate the origin of chondrocytes in the nucleus pulposus, and to document histologic findings associated with the transition of a notochordal to a fibrocartilaginous nucleus pulposus.A human nucleus pulposus undergoes a chronological transition from a notochordal to a ...
Tae-Hong Lim +5 more
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Intact rabbit lumbar intervertebral discs were examined histologically.To demonstrate the origin of chondrocytes in the nucleus pulposus, and to document histologic findings associated with the transition of a notochordal to a fibrocartilaginous nucleus pulposus.A human nucleus pulposus undergoes a chronological transition from a notochordal to a ...
Tae-Hong Lim +5 more
openaire +3 more sources