Results 111 to 120 of about 305,095 (286)

Distinct Brain Drivers and Shared Cerebello–Cortical Input in ADCY5 and SGCE Hyperkinetic Movements

open access: yesMovement Disorders, EarlyView.
Resting‐state fMRI and effective connectivity revealed distinct cerebellar–basal ganglia–cortical interactions in ADCY5 (MxMD‐ADCY5) and SGCE (MYC/DYT‐SGCE) related movement disorders. The cerebellum modulated cortex directly in MYC/DYT‐SGCE, but indirectly via basal ganglia‐cerebellar projections in MxMD‐ADCY5, which also showed reduced subthalamic ...
Clément Tarrano   +33 more
wiley   +1 more source

A Severity‐Agnostic Atrophy Pattern in Spinocerebellar Ataxia Type 3: Volumetrics from ENIGMA‐Ataxia

open access: yesMovement Disorders, EarlyView.
Background Spinocerebellar ataxia type 3 (SCA3) is a rare, inherited neurodegenerative disease characterized by progressive loss of motor coordination. Objectives We undertook a multisite magnetic resonance imaging study to profile the spatial spread of atrophy across the brain, determine whether atrophy preferentially maps onto specific functional ...
Jason W. Robertson   +43 more
wiley   +1 more source

Quantifying the impact of nuisance flooding on urban coastal communities under present and future climatic conditions: Norfolk, Virginia as a case study

open access: yesJournal of Hydrology: Regional Studies
Study region: Norfolk, Virginia, United States Study focus: Nuisance flooding, characterized by frequent but minor floods, has been on the rise and the trend is expected to continue due to climate change.
Jiwoo Jeong   +2 more
doaj   +1 more source

Testing Normal Means: The Reconcilability of the P Value and the Bayesian Evidence

open access: yesThe Scientific World Journal, 2013
The problem of reconciling the frequentist and Bayesian evidence in testing statistical hypotheses has been extensively studied in the literature. Most of the existing work considers cases without the nuisance parameters which is not the frequently ...
Yuliang Yin, Junlong Zhao
doaj   +1 more source

Quantitative Imaging of Pyruvate Metabolism in a Patient With Anaplastic Thyroid Cancer

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Magnetic resonance imaging using hyperpolarized (HP) [1‐13C]‐pyruvate enables assessment of pyruvate metabolism in vivo and offers new insight into metabolic changes in response to cancer therapy. Widely used semi‐quantitative metrics of pyruvate metabolism can be affected by physiological factors that are extrinsic to intracellular ...
James A. Bankson   +18 more
wiley   +1 more source

Super-Consistent Tests of Lp-Functional Form [PDF]

open access: yes
This paper develops a consistent test of best Lp-predictor functional form for a time series process. By functionally relating two moment conditions with different nuisance parameters we are able to construct a vector moment condition in which at least ...
Jonathan Hill
core  

A Hybrid RF Coil for Whole‐Brain Imaging in Non‐Human Primates at 7 T

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Ultra‐high field MRI (≥ 7 T) offers unprecedented potential for mapping non‐human primate (NHP) brain function. However, complex electromagnetic systems are required to meet the challenges of UHF imaging and the mechanical demands of awake NHP studies.
Elias Djaballah   +5 more
wiley   +1 more source

The Spatial Ecology of Nuisance Crocodiles: Movement Patterns of Relocated American Crocodiles (Crocodylus acutus) in Guanacaste, Costa Rica

open access: yesAnimals
Anthropogenic alterations of the environment have increased, highlighting the need for human–wildlife coexistence and conflict mitigation. Spatial ecology, and the use of passive satellite movement technology in particular, has been used to identify ...
Tyler Steven Coleman   +6 more
doaj   +1 more source

VQ‐Wave: A Physics‐Driven Spatiotemporal Deep Learning Approach for Noncontrast‐Enhanced Lung Ventilation and Perfusion MRI

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a robust deep learning framework for noncontrast‐enhanced functional lung MRI, overcoming the limitations of spectral decomposition in the presence of physiological nonstationarity. Methods We introduce VQ‐Wave (Ventilation/Q‐perfusion Waveform‐based Assessment of Variable Evolutions), a physics‐driven spatiotemporal ...
Grzegorz Bauman   +3 more
wiley   +1 more source

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