Results 121 to 130 of about 5,474,071 (364)

Quantitative null-cobordism [PDF]

Journal of the American Mathematical Society, 2018
For a given null-cobordant Riemannian n n -manifold, how does the minimal geometric complexity of a null-cobordism depend on the geometric complexity of the manifold? Gromov has conjectured that this dependence should be linear. We show that it is at most a polynomial whose degree depends on n n .
Chambers, Gregory R, Dotterrer, Dominic, Manin, Fedor, Weinberger, Shmuel   +3 more
openaire   +5 more sources

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Role of Z-pinches in magnetic reconnection in space plasmas

, 2014
A widely accepted scenario of magnetic reconnection in collisionless space plasmas is the breakage of magnetic field lines in X-points. In laboratory, reconnection is commonly studied in pinches, current channels embedded into twisted magnetic fields. No
Divin, Andrey, Lapenta, Giovanni, Markidis, Stefano, Olshevsky, Vyacheslav   +3 more
core   +1 more source

On spinors and null vectors [PDF]

Journal of Physics A: Mathematical and Theoretical, 2014
We investigate the relations between spinors and null vectors in Clifford algebra with particular emphasis on the conditions that a spinor must satisfy to be simple (also: pure). In particular we prove: i) a new property for null vectors: each of them bisects spinor space into two parts of equal size; ii) that simple spinors form one-dimensional ...
openaire   +4 more sources

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

AAPM medical physics practice guideline 13.a: HDR brachytherapy, part B

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract The goal of this report is to assist the clinical medical physicist in assuring that key quality standards and practice considerations are met to ensure safe, reliable, and reproducible high dose rate (HDR) brachytherapy (BT) treatment. This guideline has been developed to provide appropriate minimum standards for such services.
Susan L. Richardson, Arjit K. Baghwala, Gil'ad N. Cohen, Claire Dempsey, Bruce Libby, Christopher S. Melhus, Robin A. Miller, Daniel J. Scanderbeg, Samantha J. Simiele   +8 more
wiley   +1 more source

Serotonergic and Dopaminergic Function in Neuropsychiatrically Asymptomatic People With HIV on Antiretroviral Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with HIV (PWH) on antiretroviral therapy (ART) still experience neurocognitive dysfunction and accelerated brain volume loss. To assess whether the serotonergic and dopaminergic systems are affected, we used [11C]DASB positron emission tomography (PET) to assess presynaptic serotonergic function and [18F]FDOPA PET to measure ...
Chuen‐Yen Lau, Anna Lyndaker, Swati Shah, Paul Wakim, Amelia Mitchell, Cynthia Monroe, Alan Kim, Tracy L. Cropper, Govind Nair, Joseph Snow, Bryan R. Smith, Avindra Nath, Dima A. Hammoud   +12 more
wiley   +1 more source

Coffee Consumption Is Associated With Later Age‐at‐Onset of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Observation studies suggest that coffee consumption may lower the risk and delay the age‐at‐onset (AAO) of Parkinson's disease (PD). The aim of this study was to explore the causal relationship and genetic association between coffee consumption and the AAO, risk, and progression of PD. Using Mendelian randomization, we identified a significant
Dariia Kuzovenkova, Lang Liu, Ziv Gan‐Or, Konstantin Senkevich   +3 more
wiley   +1 more source

A Systematic Clinical Framework for Postimplantation Monitoring in Thalamic Neuromodulation: Insights From Twiddler's Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This case described a 25‐year‐old pregnant woman with refractory multifocal epilepsy, diagnosed in 2020 and treated with bilateral thalamic deep brain stimulation (DBS) targeting the centromedian and pulvinar nuclei. Prior to DBS, she experienced daily focal seizures, often progressing to generalized tonic–clonic seizures despite optimal ...
Shalin Shah, Ganne Chaitanya, Jeston Chin, Nicholas Delcimmuto, Jay R. Gavvala   +4 more
wiley   +1 more source

TBX6 null variants and a common hypomorphic allele in congenital scoliosis.

New England Journal of Medicine, 2015
BACKGROUND Congenital scoliosis is a common type of vertebral malformation. Genetic susceptibility has been implicated in congenital scoliosis. METHODS We evaluated 161 Han Chinese persons with sporadic congenital scoliosis, 166 Han Chinese controls ...
N. Wu, X. Ming, J. Xiao, Z. Wu, X. Chen, M. Shinawi, Y. Shen, G. Yu, J. Liu, H. Xie, Z. Gucev, S. Liu, N. Yang, H. Al-Kateb, J. Chen, Jian Zhang, N. Hauser, T. Zhang, V. Tasic, P. Liu, X. Su, X. Pan, C. Liu, L. Wang, Joseph Shen, Jianxiong Shen, Y. Chen, Jianguo Zhang, K. W. Choy, Jun Wang, Q. Wang, S. Li, Wei Zhou, J. Guo, Y. Wang, C. Zhang, H. Zhao, Y. An, Yang Zhao, Jiucun Wang, Z. Liu, Y. Zuo, Y. Tian, X. Weng, V. R. Sutton, Hong Wang, Y. Ming, S. Kulkarni, T. P. Zhong, P. Giampietro, S. Dunwoodie, S. W. Cheung, X. Zhang, L. Jin, J. Lupski, G. Qiu, F. Zhang   +56 more
semanticscholar   +1 more source