Results 161 to 170 of about 76,267 (236)

Cross‐Linking Matters: Atomistic Simulations of the Thermal Degradation of Polymethylsiloxanes

open access: yesAdvanced Theory and Simulations, EarlyView.
Atomistic simulations reveal how cross‐linking of polysiloxanes governs degradation pathways, gas evolution, and mass retention. Abstract Utilizing an advanced machine‐learning interatomic potential (MLIP) for Si─C─O─H, the thermal breakdown of polysiloxanes covering polymers from linear polydimethylsiloxane (PDMS) to highly networked ...
Mitchell Falgoust, Peter Kroll
wiley   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan   +20 more
wiley   +1 more source

Advances in gene therapy for Lafora disease: Intravenous recombinant adeno-associated virus-mediated delivery of EPM2A and EPM2B genes. [PDF]

open access: yesClin Transl Med
Zafra-Puerta L   +8 more
europepmc   +1 more source

Laser Ultrasound Super‐Resolution Imaging for Multi‐Parametric Non‐Invasive Volumetric Characterization of Brain Cancer

open access: yesAdvanced Science, EarlyView.
Laser ultrasound super‐resolution imaging (LUSSI) leverages laser‐generated ultrasound for functional 3D transcranial imaging of brain tumor vasculature. Combined with optoacoustic tomography, it is demonstrated in a glioblastoma model, revealing structural abnormalities, compressed vessels, hemorrhages, and hypoxic regions.
Daniil Nozdriukhin   +4 more
wiley   +1 more source

A polymorphic inframe deletion in the ODR-10 extracellular loop 2 abolishes diacetyl sensing. [PDF]

open access: yesMicroPubl Biol
Mehraj A   +4 more
europepmc   +1 more source

Development of a 3D Human Colon Model Along with Bioelectronics for the Induction and Monitoring of Diseases

open access: yesAdvanced Science, EarlyView.
We present a functional three‐dimensional in‐vivo‐mimicking human colon (3D‐IVM‐HC) model engineered via Freeform Reversible Embedding of Suspended Hydrogels bioprinting with gelatin methacrylate (GelMA)/alginate hydrogels. This 3D non‐animal model replicates crypt‐like architectures, epithelial polarization, and stromal–tumor interactions, showing ...
Jorge Alfonso Tavares‐Negrete   +7 more
wiley   +1 more source

Exploring the structure of the school curriculum with graph neural networks. [PDF]

open access: yesJ Comput Soc Sci
Garzón B   +4 more
europepmc   +1 more source

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