The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon +6 more
wiley +1 more source
Coconut: covariate-assisted composite null hypothesis testing with applications to replicability analysis of high-throughput experimental data. [PDF]
Li Y, Li Y, Ma H, Yue Z, Zhang X.
europepmc +1 more source
Three new atomic/molecular layer deposition processes are developed for Co‐organic thin films using a promising all‐nitrogen‐coordinated cobalt precursor. The study examines film growth, reaction mechanisms, chemical stability, and decomposition pathways of the resulting films through extensive characterization techniques and DFT calculations ...
Topias Jussila +9 more
wiley +1 more source
Structural variation detection with read pair information — An improved null-hypothesis reduces bias [PDF]
Kristoffer Sahlin +2 more
openalex +1 more source
Non‐Invasive Multidimensional Capacitive Sensing for In Vivo Traumatic Brain Injury Monitoring
Single‐electrode, multidimensional capacitive sensors noninvasively assess cerebral autoregulation and compliance for traumatic brain injury monitoring. ABSTRACT Traumatic brain injury (TBI) is a major cause of death and disability, but invasive intracranial pressure (ICP) monitoring is risky, and current non‐invasive methods lack the resolution and ...
Shawn Kim +8 more
wiley +1 more source
Ready to ROC? A tutorial on simulation-based power analyses for null hypothesis significance, minimum-effect, and equivalence testing for ROC curve analyses. [PDF]
Riesthuis P, Otgaar H, Bücken C.
europepmc +1 more source
Informative hypotheses: How to move beyond classical null hypothesis testing
Rens van de Schoot
openalex +1 more source
Pak Biawak, a necrobot, embodies an unusual fusion of biology and robotics. Designed to repurpose natural structures after death, it challenges conventional boundaries between nature and engineering. Its movements are precise yet unsettling, raising questions about sustainability, ethics, and the untapped potential of biointegrated machines.
Leo Foulds +2 more
wiley +1 more source
Comparing researchers' degree of dichotomous thinking using frequentist versus Bayesian null hypothesis testing. [PDF]
Muradchanian J +4 more
europepmc +1 more source
Corrigendum: Searching for the Critical p of Macphail's Null Hypothesis: The Contribution of Numerical Abilities of Fish. [PDF]
Miletto Petrazzini ME +3 more
europepmc +1 more source

