Results 51 to 60 of about 878,195 (332)
Null-Space Preconditioners for Saddle Point Systems [PDF]
SIAM Journal on Matrix Analysis and Applications, 2016 Summary: The null-space method is a technique that has been used for many years to reduce a saddle point system to a smaller, easier to solve, symmetric positive definite system. This method can be understood as a block factorization of the system.
Pestana, Jennifer, Rees, Tyrone
openaire +2 more sources
Superselection Sectors in Asymptotic Quantization of Gravity [PDF]
, 1996 Using the continuity of the scalar $\Psi_2$ (the mass aspect) at null infinity through $i_o$ we show that the space of radiative solutions of general relativity can be thought of a fibered space where the value of $\Psi_2$ at $i_o$ plays the role of the ...
Dominguez, Alfredo E. +2 more
core +3 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
A Null Space Sensitivity Analysis for Hydrological Data Assimilation with Ensemble Methods
HydrologyPredictive uncertainty analysis focuses on defensible variability in model projected values after estimation of the posterior parameter distribution.
Nick Martin, Jeremy White, Paul Southard
doaj +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
ON NULL CURVES ON SURFACES AND NULL VECTORS IN LORENTZ SPACE
Süleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2009 : In this work, we compare the Darboux frame and the Frenet frame of a null curve lying on a spacelike surface in the three-dimensional Lorentz space, and we show that the normal curvature of the curve is a constant.
A. Ceylan ÇÖKEN
doaj
IEEE AccessThis paper proposes a peak-to-average power ratio (PAPR) reduction method that utilizes the null space in a multiple-input multiple-output (MIMO) channel for downlink MIMO-orthogonal frequency division multiplexing (OFDM) signals with multiple-antenna ...
Asuka Kakehashi +2 more
doaj +1 more source