Programmable Carrier‐Free All‐Enzyme Beads for Modular Continuous‐Flow Biocatalysis
Genetically encoded enzyme building blocks self‐assemble into monodisperse, carrier‐free protein beads via a droplet‐based formulation strategy. These programmable catalytic particles enable modular continuous‐flow biocatalysis, from single‐enzyme reactions to multi‐enzyme cascades and bead–bead coupled reactor systems.
Jennifer Kühne +12 more
wiley +1 more source
Neuronal activity and amyloid-β promote tau seeding in the entorhinal cortex in Alzheimer's disease. [PDF]
Alexandersen CG +3 more
europepmc +1 more source
To address functionality limitations in plant‐based and industrially compostable polymer aerogels, this work introduces bio‐inspired aerogels with broadened functionality. Inspired by functional plant tissues, lightweight biopolymer aerogels based on exclusively stereocomplex crystals are fabricated, featuring hierarchically macro‐/meso‐porous ...
Anthony V. Tuccitto +10 more
wiley +1 more source
Melt electrofibrillation (MEF) enables the fabrication of nanofibrillar PCL scaffolds with defined architectures that guide cellular alignment and retention during cartilage tissue engineering. Unlike conventional melt electrowriting, MEF consistently directs collagen type II‐rich extracellular matrix organization, providing a tunable platform to ...
Alba Pueyo Moliner +10 more
wiley +1 more source
How painful is Implanon NXT<sup>®</sup> insertion?: A multicenter randomized trial on the use of Acetaminophen, Mefenamic Acid and Diclofenac Sodium for pain management post Implanon NXT<sup>®</sup> insertion. [PDF]
Nik Azis NA +9 more
europepmc +1 more source
Breaking Bottlenecks in Solid Electrolyte Discovery With Large Artificial Intelligence Models
Large AI models are presented as a route to break key bottlenecks in solid electrolyte discovery by linking materials databases, machine‐learning interatomic potentials, large language models, and autonomous experiments. This perspective highlights how AI can accelerate the identification of solid electrolytes with fast ion transport, stable interfaces,
Eric Jianfeng Cheng +24 more
wiley +1 more source
Large language models for promoting physical activity: a review of experiential and behavioral outcomes, social roles, and human-likeness in persuasive LLMs. [PDF]
Silacci A, Boldi A, Caon M, Rapp A.
europepmc +1 more source
Phase Diagrams Enable Solid‐State Battery Design
Batteries are non‐equilibrium devices with inherent thermodynamic driving forces to react at interfaces, regardless of kinetics or operating conditions. Chemical potential mismatches across interfaces are dissipated via interfacial reactions. In this work, it is illustrated how phase diagrams and chemical potential maps predict degradation pathways but
Nathaniel L. Skeele, Matthias T. Agne
wiley +1 more source
Mediterranean PAH Stratification in Phenylketonuria: Tracing Historical Maps to Point Toward Clinical Phenotype and Obesity Risk. [PDF]
Tummolo A +7 more
europepmc +1 more source

