Results 61 to 70 of about 512,275 (295)

The effect of verbal agreement marking on the use of null and overt subjects: a quantitative study of first person singular in Brazilian Portuguese

Fórum Linguístico, 2019
In a corpus study and two acceptability experiments, we investigated whether there is a preference for null or overt subjects with ambiguous (syncretic) and exclusive (unambiguous) verbs in Brazilian Portuguese (BP).
Eduardo Correa Soares, Philip H. Miller, Barbara Hemforth   +2 more
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity [PDF]

Genomics & Informatics, 2018
In this report, we present a case study of how pharmacogenomics and pharmacometabolomics can be useful to characterize safety and pharmacokinetic profiles in early phase new drug development clinical trials. During conducting a first-in-human trial for a
Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang   +7 more
doaj   +1 more source

The analysis of very small samples of repeated measurements II: a modified box correction [PDF]

, 2010
There is a need for appropriate methods for the analysis of very small samples of continuous repeated measurements. A key feature of such analyses is the role played by the covariance matrix of the repeated observations.
Bellavance, Box, Box, Brammer, Chen, Crowder, Fitzmaurice, Geisser, Greenhouse, Huynh, Jones, Kenward, Kenward, Mancl, Nelder, Nelder, Pan, SAS Institute Inc., Satterthwaite, Scheffé, Skene, Stuart, Verbeke   +22 more
core   +2 more sources

Null Referential Subjects in Övdalian

Nordic Journal of Linguistics, 2010
This article is concerned with the description and analysis of Övdalian referential null subjects. A general background to Övdalian is provided together with the syntactic restrictions on the possible null subjects (wįð‘we’ andið‘you’). Interestingly, these null subjects in Övdalian do not appear in the same syntactic positions.
openaire   +2 more sources

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

Robust regression for large-scale neuroimaging studies [PDF]

, 2015
Multi-subject datasets used in neuroimaging group studies have a complex structure, as they exhibit non-stationary statistical properties across regions and display various artifacts.
,, Banaschewski, Tobias, Barker, Gareth J, Bokde, Arun L W, Brühl, Rüdiger, Butzek, Brigitte, Conrod, Patricia, Da Mota, Benoit, Flor, Herta, Fritsch, Virgile, Frouin, Vincent, Garavan, Hugh, Lemaitre, Hervé, Loth, Eva, Mann, Karl, Nees, Frauke, Paus, Tomas, Poline, Jean-Baptiste, Schad, Daniel J, Schümann, Gunter, Thirion, Bertrand, Varoquaux, Gaël   +21 more
core   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Remarks on Finite Control and Hyper-Raising in Brazilian Portuguese

Journal of Portuguese Linguistics, 2019
In this reply I examine Modesto’s (2011) claim that null subjects in Brazilian Portuguese (BP) are not controlled and are not derived by movement.
Jairo Nunes
doaj   +2 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source