Results 81 to 90 of about 18,597,770 (234)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Singed Total Domatic Number of a Graph [PDF]

open access: yes, 2010
The maximum number of functions in a signed total dominating family on G is the signed total domatic number of G. In this paper, some properties related signed total domatic number and signed total domination number of a graph are studied and found the ...
Shailaja S. Shirkol   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Ocular drift along the mental number line [PDF]

open access: yes, 2016
We examined the spontaneous association between numbers and space by documenting attention deployment and the time course of associated spatial-numerical mapping with and without overt oculomotor responses.
Angelo Cangelosi   +14 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Peculiarities of Grammatical Properties in Nominal Word Combinations

open access: yesVestnik MGIMO-Universiteta, 2014
The article examines some peculiarities if grammatical properties of nominal word combinations based on the study of German-speaking Swiss press. The accumulated experience of linguists is analyzed and certain factors influencing the choice of syntactic ...
Irina B. Klienkova
doaj  

Das competências quantitativas iniciais para o conceito de número natural: quais as trilhas possíveis? From quantitative abilities to natural number concept: what are the possible pathways?

open access: yesPsicologia: Reflexão e Crítica, 2012
A presente revisão tem o objetivo de analisar as propostas apresentadas por estudos na área da cognição matemática sobre as habilidades quantitativas iniciais dos bebês e como estas habilidades iniciais podem levar à construção do conceito de número ...
Heloiza H. Barbosa
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Prandtl Number of Toroidal Plasmas [PDF]

open access: yes, 1993
Theory of the L-mode confinement in toroidal plasmas is developed. The Prandtl number , the ratio between the ion viscosity and the thermal conductivity is obtained for the anomalous transport process which is caused by the self-sustained turbulence in ...
Itoh, S.-I.   +4 more
core  

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