Results 241 to 250 of about 11,325,403 (303)

Propagation effects in high harmonic generation media driven by bright squeezed vacuum light. [PDF]

Nat Commun
Rivera-Dean J, Kanti D, Stammer P, Carlström S, Tsatrafyllis N, Ivanov MY, Lewenstein M, Tzallas P.   +7 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

A global dataset of key traits for plant belowground functioning. [PDF]

Sci Data
Bruelheide H, Andraczek K, Bombo AB, Damasceno G, Fan Y, Freschet GT, Hartmann L, Hennecke J, Howard CC, Jimoh SO, Klimešová J, Laughlin DC, Mommer L, Ramalevha T, Siebert F, Tumber-Dávila SJ, Weigelt A, Atkins D, Bonari G, Carter TA, Doležal J, Harris T, Jiménez-Alfaro B, Kelly AR, Lubbe FC, Martínková J, Millan M, Ott J, Orzell S, Qian J, Stears AE, Whigham D, Jing X, Bergmann J, Fidelis A.   +34 more
europepmc   +1 more source

On the Genus Fields of Pure Number Fields II

Tokyo Journal of Mathematics, 1981
openaire   +3 more sources

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

The Neurobehavioral Profile of Phelan-McDermid Syndrome: Suggestions for Assessment Tools in Light of the 2023 Consensus Guidelines. [PDF]

Genes (Basel)
Payne E, Sarasua SM, Rogers C, Martin R, Phelan K, Beamer L, Boccuto L.   +6 more
europepmc   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Spin effects in superfluidity, neutron matter, and neutron stars. [PDF]

Sci Adv
Sedrakian A, Rau PB.
europepmc   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source