Results 131 to 140 of about 58,715 (251)

The effect of frailty on hospitalisation trajectories in adults aged 65 and older across 10 European countries: a 14-year longitudinal analysis from the Survey of Health, Ageing, and Retirement in Europe (SHARE). [PDF]

Eur J Ageing
Woldemariam S, Stolz E, Stein KV, Haider S, Dorner TE.   +4 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Skilled Nursing Facility Utilization Among Community-Dwelling Older Adults With Alzheimer's Disease and Related Dementias During the COVID-19 Pandemic. [PDF]

J Am Med Dir Assoc
Ying M, Cheng Z, Hirth RA, Hollenbeck BK, Joynt Maddox KE, Shahinian VB, Li Y.   +6 more
europepmc   +1 more source

Porto under pressure: spatial and temporal insights of the accelerated growth of tourism

In 2022, the capacity of tourist accommodation in the municipality of Porto, Portugal, corresponded to 5.7% of the national total, 31.9% of the total for the northern region and 60.9% of the Porto Metropolitan Area (Pordata, 2024).
Costa, Rui Augusto da, Martins, Márcio Ribeiro, Costa, Adriano, Correia, Ricardo   +3 more
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Hospitalization profile among pediatric populations with type 1 diabetes mellitus in Australia: An ecological study. [PDF]

Medicine (Baltimore)
Naser AY, Alwafi H, Alsharif AA, Al Rajeh AM, Alqahtani JS, Aldhahir AM, Jarab AS, Alkhatib NS, Alhartani YJ, El-Qasem A.   +9 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Tobacco Smoke Exposure Biomarker Profiles and Healthcare Utilization Patterns Among U.S. Children. [PDF]

Toxics
Merianos AL, Matt GE, Jandarov RA, Mahabee-Gittens EM.   +3 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Redefining eligibility for same-day discharge after mastectomy: safety, feasibility, and clinical insights. [PDF]

Ann Med Surg (Lond)
Ishimwe Mugisha A.
europepmc   +1 more source